Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

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Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

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Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

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type

Item

label

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

@en

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

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prefLabel

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

@en

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development.

@nl

P1476

Reviewing the Utility of Two Species in General Toxicology Related to Drug Development

@en

P2093

Elisabeth Mortimer-Cassen

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Helen Prior

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Ian Kimber

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Keith Jones

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Lolke de Haan

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Noel Downes

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Paul Baldrick

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P2860

Preclinical development of monoclonal antibodies: considerations for the use of non-human primates

Concordance of the toxicity of pharmaceuticals in humans and in animals.

Safety evaluation to support First-In-Man investigations II: toxicology studies.

Drug development and nonclinical to clinical translational databases: past and current efforts.

Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use.

Predicting toxicities in humans by nonclinical safety testing: an update with particular reference to anticancer compounds.

Role of chronic toxicology studies in revealing new toxicities.

Potentials and limitations of nonclinical safety assessment for predicting clinical adverse drug reactions: correlation analysis of 142 approved drugs in Japan.

The Use of Minipigs for Preclinical Safety Assessment by the Pharmaceutical Industry: Results of an IQ DruSafe Minipig Survey.

Current nonclinical testing paradigm enables safe entry to First-In-Human clinical trials: The IQ consortium nonclinical to clinical translational database.

P304

121-124

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P31

scholarly article

P356

10.1177/1091581818760564

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2018-03-27T00:00:00Z

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P932

5881785

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