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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesNatural killer cells promote early CD8 T cell responses against cytomegalovirusSelective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2DLymphocyte activation via NKG2D: towards a new paradigm in immune recognition?Expression of human NKRP1A by CD34+ immature thymocytes: NKRP1A-mediated regulation of proliferation and cytolytic activityGene structure, expression pattern, and biological activity of mouse killer cell activating receptor-associated protein (KARAP)/DAP-12Identity, regulation and in vivo function of gut NKp46+RORγt+ and NKp46+RORγt- lymphoid cells.Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptorMultiplicity and plasticity of natural killer cell signaling pathways.Coordination of activating and inhibitory signals in natural killer cells.KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions.Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infectionMapping of NKp46(+) Cells in Healthy Human Lymphoid and Non-Lymphoid TissuesThe trafficking of natural killer cells.Essential role of DAP12 signaling in macrophage programming into a fusion-competent state.Natural killer cells: detectors of stress.A novel dendritic cell subset involved in tumor immunosurveillance.Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells.Contrasting roles of DAP10 and KARAP/DAP12 signaling adaptors in activation of the RBL-2H3 leukemic mast cell line.NKRP1A and p40 molecules are involved in regulation of activation and maturation of human NK cells.Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases.Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin.Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways.Impaired synaptic function in the microglial KARAP/DAP12-deficient mouse.Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor.Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral InfectionIncreased diabetes development and decreased function of CD4+CD25+Treg in the absence of a functional DAP12 adaptor proteinIntestinal innate immune cells in gut homeostasis and immunosurveillancePeripheral natural killer cells exhibit qualitative and quantitative changes in patients with psoriasis and atopic dermatitisp40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes
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description
hulumtuese
@sq
researcher
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wetenschapper
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հետազոտող
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name
Elena Tomasello
@ast
Elena Tomasello
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Elena Tomasello
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Elena Tomasello
@nl
Elena Tomasello
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type
label
Elena Tomasello
@ast
Elena Tomasello
@en
Elena Tomasello
@es
Elena Tomasello
@nl
Elena Tomasello
@sl
prefLabel
Elena Tomasello
@ast
Elena Tomasello
@en
Elena Tomasello
@es
Elena Tomasello
@nl
Elena Tomasello
@sl
P106
P1153
6701338990
P21
P31
P496
0000-0002-6839-5219