about
A proteome-scale map of the human interactome networkA DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactomeNetwork-based in silico drug efficacy screeningAn inter-species protein-protein interaction network across vast evolutionary distanceNetwork-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits.From comorbidities of chronic obstructive pulmonary disease to identification of shared molecular mechanisms by data integration.A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary DiseaseDisease networks. Uncovering disease-disease relationships through the incomplete interactomeA disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthmaA combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor.Canonical genetic signatures of the adult human brain.Endophenotype Network Models: Common Core of Complex Diseases.Tissue Specificity of Human Disease Module.Integrating personalized gene expression profiles into predictive disease-associated gene poolsSystems Medicine: from molecular features and models to the clinic in COPD.Human symptoms-disease network.A systems biology approach to cGMP suggests a prominent role for sGC in stroke: Validation by mechanism-based activation of apo-sGC in non-steal dosing coveys neuroprotection and increased survival.Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.The immune system as a social network.A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.Network medicine: a new paradigm for cardiovascular disease research and beyond.Asymptotic properties of degree-correlated scale-free networks.Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network EndopharmacologyIntegration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network ModuleBAFF Neutralization Aggravates AtherosclerosisMapping the Human Kinome in Response to DNA DamageNon-classical monocytes as mediators of tissue destruction in arthritisSequences of phase transitions in Ising models on correlated networksQuantifying a certain ''advantage law'': minority game with above the rules agentsGermline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulationMapping the perturbome network of cellular perturbationsType I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell FunctionMutational landscape of the transcriptome offers putative targets for immunotherapy of myeloproliferative neoplasmsHACE1 deficiency leads to structural and functional neurodevelopmental defectsMTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulationSystematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancersPlasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jörg Menche
@ast
Jörg Menche
@en
Jörg Menche
@es
Jörg Menche
@nl
Jörg Menche
@sl
type
label
Jörg Menche
@ast
Jörg Menche
@en
Jörg Menche
@es
Jörg Menche
@nl
Jörg Menche
@sl
prefLabel
Jörg Menche
@ast
Jörg Menche
@en
Jörg Menche
@es
Jörg Menche
@nl
Jörg Menche
@sl
P108
P1053
G-3994-2015
P106
P21
P31
P496
0000-0002-1583-6404