about
Structural and mechanistic insight into N-glycan processing by endo-α-mannosidaseEngineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal AntibodiesNon-specific accumulation of glycosphingolipids in GNE myopathyMinimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig ModelSynthesis and biological characterisation of novel N-alkyl-deoxynojirimycin alpha-glucosidase inhibitors.Heart failure in a woman with SLE, anti-phospholipid syndrome and Fabry's disease4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group.Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.A Novel Iminosugar UV-12 with Activity against the Diverse Viruses Influenza and Dengue (Novel Iminosugar Antiviral for Influenza and Dengue)Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.Iminosugars Inhibit Dengue Virus Production via Inhibition of ER Alpha-Glucosidases--Not Glycolipid Processing Enzymes.Structures of mammalian ER α-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals.Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4.Urinary glycan markers for disease.Iminosugar antivirals: the therapeutic sweet spot.Restricted processing of glycans by endomannosidase in mammalian cells.Inhibitors of endoplasmic reticulum alpha-glucosidases potently suppress hepatitis C virus virion assembly and releaseSmall molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses.An iminosugar with potent inhibition of dengue virus infection in vivo.Novel imino sugar α-glucosidase inhibitors as antiviral compounds.Hydrophilic interaction liquid chromatography of anthranilic acid-labelled oligosaccharides with a 4-aminobenzoic acid ethyl ester-labelled dextran hydrolysate internal standard.Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum α-glucosidase inhibitionSynthesis and α-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis
P50
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P50
description
onderzoeker
@nl
researcher
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հետազոտող
@hy
name
D Alonzi
@ast
D Alonzi
@en
D Alonzi
@es
D Alonzi
@nl
D Alonzi
@sl
type
label
D Alonzi
@ast
D Alonzi
@en
D Alonzi
@es
D Alonzi
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D Alonzi
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prefLabel
D Alonzi
@ast
D Alonzi
@en
D Alonzi
@es
D Alonzi
@nl
D Alonzi
@sl
P106
P1153
23481226900
P31
P496
0000-0002-1330-9109