about
Development of rapid staining protocols for laser-capture microdissection of brain vessels from human and rat coupled to gene expression analyses.Expression of human hepatic lipase negatively impacts apolipoprotein A-I production in primary hepatocytes from Lipc-null mice.APOE and APOC1 gene polymorphisms are associated with cognitive impairment progression in Chinese patients with late-onset Alzheimer's disease.Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes.DNA strand exchange catalyzed by proteins from vaccinia virus-infected cells.Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging.The in vitro bioassay systems for the amplification and detection of abnormal prion PrP(Sc) in blood and tissues.Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.Rapid and accurate in vitro assays for detection of West Nile virus in blood and tissues.Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer's diseaseABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease.DNA strand transfer catalyzed by the 5'-3' exonuclease domain of Escherichia coli DNA polymerase I.Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer's disease.Increased expression of bioactive chemokines in human cerebromicrovascular endothelial cells and astrocytes subjected to simulated ischemia in vitro.DNA binding and aggregation properties of the vaccinia virus I3L gene product.Frequent loss of heterozygosity on chromosomes 16 and 4 in human hepatocellular carcinoma.Vaccinia virus DNA polymerase promotes DNA pairing and strand-transfer reactions.[Hypoxia induced by CoCl2 influencing the expression and the activity of matrix metalloproteinase-2 in rat hepatic stellate cells].Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg-SwDI transgenic mice.Indomethacin and cyclosporin a inhibit in vitro ischemia-induced expression of ICAM-1 and chemokines in human brain endothelial cells.Prediction of brain:blood unbound concentration ratios in CNS drug discovery employing in silico and in vitro model systemsInflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1betaQuantitative Algorithm-Based Paired Imaging Measurement for Antibody-Triggered Endocytosis in Cultured CellsDevelopment of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Wandong Zhang
@ast
Wandong Zhang
@en
Wandong Zhang
@es
Wandong Zhang
@nl
Wandong Zhang
@sl
type
label
Wandong Zhang
@ast
Wandong Zhang
@en
Wandong Zhang
@es
Wandong Zhang
@nl
Wandong Zhang
@sl
prefLabel
Wandong Zhang
@ast
Wandong Zhang
@en
Wandong Zhang
@es
Wandong Zhang
@nl
Wandong Zhang
@sl
P108
P106
P108
P31
P496
0000-0001-6412-8124