No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.
about
Expression of gamma-glutamylcysteine synthetase (gamma-GCS) and multidrug resistance-associated protein (MRP), but not human canalicular multispecific organic anion transporter (cMOAT), genes correlates with exposure of human lung cancers to platinuLow-level resistance to camptothecin in a human small-cell lung cancer cell line without reduction in DNA topoisomerase I or drug-induced cleavable complex formation.Identification of gene polymorphisms of human DNA topoisomerase I in the National Cancer Institute panel of human tumour cell lines.New Topoisomerase I mutations are associated with resistance to camptothecinEffects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan.Role of ABCG2 as a biomarker for predicting resistance to CPT-11/SN-38 in lung cancer.The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro.Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.CPT-11 may provide therapeutic efficacy for esophageal squamous cell cancer and the effects correlate with the level of DNA topoisomerase I protein.Expression of drug resistance-related genes in head and neck squamous cell carcinomas and normal mucosa.Differential expression of DNA topoisomerase II alpha and II beta genes between small cell and non-small cell lung cancer.
P2860
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P2860
No alteration in DNA topoisomerase I gene related to CPT-11 resistance in human lung cancer.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
No alteration in DNA topoisome ...... sistance in human lung cancer.
@en
No alteration in DNA topoisome ...... sistance in human lung cancer.
@nl
type
label
No alteration in DNA topoisome ...... sistance in human lung cancer.
@en
No alteration in DNA topoisome ...... sistance in human lung cancer.
@nl
prefLabel
No alteration in DNA topoisome ...... sistance in human lung cancer.
@en
No alteration in DNA topoisome ...... sistance in human lung cancer.
@nl
P2093
P2860
P1476
No alteration in DNA topoisome ...... sistance in human lung cancer.
@en
P2093
P2860
P304
P356
10.1111/J.1349-7006.1996.TB03144.X
P577
1996-12-01T00:00:00Z