Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

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The Pathogenesis and Therapies of Striated Muscle Laminopathies

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Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@en

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@nl

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Item

label

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@en

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@nl

prefLabel

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@en

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@nl

P1476

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

@en

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Amanda J DuBose

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Leslie B Gordon

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Michael R Erdos

http://www.w3.org/2001/XMLSchema#string

Noreen M Petrash

http://www.w3.org/2001/XMLSchema#string

Stephen T Lichtenstein

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Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy

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Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

Phenotype and course of Hutchinson-Gilford progeria syndrome

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

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A global reference for human genetic variation

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scholarly article

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10.1073/PNAS.1802811115

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English

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115

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Francis Collins

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2018-03-26T00:00:00Z

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29581305

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5910873

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Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

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P2860

P2860

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

description

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type

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P1433

P1476

P2093

P2860

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P356

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P698

P932

P356

P1433

P1476

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P31

P356

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P50

P577

P698

P932