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Mapping intact protein isoforms in discovery mode using top-down proteomicsTop-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometersTop Down Proteomics Reveals Mature Proteoforms Expressed in Subcellular Fractions of the Echinococcus granulosus Preadult StageTop-down proteomics with mass spectrometry imaging: a pilot study towards discovery of biomarkers for neurodevelopmental disordersBone protein "extractomics": comparing the efficiency of bone protein extractions of Gallus gallus in tandem mass spectrometry, with an eye towards paleoproteomicsMass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensisThe first pilot project of the consortium for top-down proteomics: a status report.ProSight Lite: graphical software to analyze top-down mass spectrometry dataBioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite.Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.Fragmentation of integral membrane proteins in the gas phase.Deciphering the late biosynthetic steps of antimalarial compound FR-900098.Applying label-free quantitation to top down proteomics.Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDaThe C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomicsKinetics of re-establishing H3K79 methylation marks in global human chromatin.Site-specific human histone H3 methylation stability: fast K4me3 turnoverHigh-definition de novo sequencing of crustacean hyperglycemic hormone (CHH)-family neuropeptidesThe MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.Deep and quantitative top-down proteomics in clinical and translational researchOn the scalability and requirements of whole protein mass spectrometryFungal artificial chromosomes for mining of the fungal secondary metabolomeDefining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multidimensional Mass Spectrometry-Based Platform.Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein.Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS.Top down proteomics of human membrane proteins from enriched mitochondrial fractionsIntegrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts.Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression.Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection.Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociationGatekeeping versus promiscuity in the early stages of the andrimid biosynthetic assembly line.Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.Developing top down proteomics to maximize proteome and sequence coverage from cells and tissues.Ultraviolet photodissociation for characterization of whole proteins on a chromatographic time scale.Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients.Loss of BAP1 function leads to EZH2-dependent transformation.High-Throughput Analysis of Intact Human Proteins Using UVPD and HCD on an Orbitrap Mass Spectrometer.
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researcher
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wetenschapper
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հետազոտող
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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Paul M. Thomas
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0000-0003-2887-4765