about
Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cellsCombination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.Design, synthesis, and biological evaluation of triazolo-pyrimidine derivatives as novel inhibitors of hepatitis B virus surface antigen (HBsAg) secretion.Synthesis and Anti-HCV Activity of a Novel 2',3'-Dideoxy-2'-α-fluoro-2'-β-C-methyl Guanosine Phosphoramidate Prodrug.Novel substituted aminothiazoles as potent and selective anti-hepatocellular carcinoma agents.Synthesis and biological evaluation of 4-substituted fluoronucleoside analogs for the treatment of hepatitis B virus infection.Anti-hepatitis B virus activity of α-DDB-FNCG, a novel nucleoside-biphenyldicarboxylate compound in vitro and in vivo.Anti-hepatitis B virus activity of α-DDB-DU, a novel nucleoside analogue, in vitro and in vivo.Investigation of the Interaction between 1,3-Diazaheterocyclic Compounds and the Fat Mass and Obesity-Associated Protein by Fluorescence Spectroscopy and Molecular Modeling.Design, synthesis, and biological evaluation of N-alkylated deoxynojirimycin (DNJ) derivatives for the treatment of dengue virus infection.Inhibitors of endoplasmic reticulum alpha-glucosidases potently suppress hepatitis C virus virion assembly and releaseSmall molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses.Design, synthesis, and biological evaluation of new N(4)-Substituted 2'-deoxy-2'-fluoro-4'-azido cytidine derivatives as potent anti-HBV agents.Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO).Synthesis and biological evaluation of a novel β-D-2'-deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine phosphoramidate prodrug for the treatment of hepatitis C virus infection.Synthesis of novel strobilurin-pyrimidine derivatives and their antiproliferative activity against human cancer cell lines.Design, synthesis, and biological evaluation of new 1,2,3-triazolo-2'-deoxy-2'-fluoro- 4'-azido nucleoside derivatives as potent anti-HBV agents.Identification of the binding between three fluoronucleoside analogues and fat mass and obesity-associated protein by isothermal titration calorimetry and spectroscopic techniques.Synthesis of 5-Amino and 3,5-Diamino Substituted 1,2,4-Thiadiazoles by I2-Mediated Oxidative N-S Bond Formation.I2-Mediated Intramolecular C-H Amidation for the Synthesis of N-Substituted Benzimidazoles.Synthesis of Novel Imidazo[1,2-a]pyridin-2-amines from Arylamines and Nitriles via Sequential Addition and I2 /KI-Mediated Oxidative Cyclization.Synthesis of Quinazolines from N,N'-Disubstituted Amidines via I2/KI-Mediated Oxidative C-C Bond Formation.Iodine/Copper Iodide-Mediated C-H Functionalization: Synthesis of Imidazo[1,2-a]pyridines and Indoles from N-Aryl Enamines.Synthesis of 1,2,4-Triazolo[4,3-a]pyridines and Related Heterocycles by Sequential Condensation and Iodine-Mediated Oxidative Cyclization.A Novel Inhibitor of the Obesity-Related Protein FTO.I2/KI-Mediated Oxidative N-N Bond Formation for the Synthesis of 1,5-Fused 1,2,4-Triazoles from N-Aryl Amidines.PIDA-mediated oxidative C-C bond formation: novel synthesis of indoles from N-aryl enaminesI2-mediated oxidative C-N bond formation for metal-free one-pot synthesis of di-, tri-, and tetrasubstituted pyrazoles from α,β-unsaturated aldehydes/ketones and hydrazinesSynthesis of 2-amino-1,3,4-oxadiazoles and 2-amino-1,3,4-thiadiazoles via sequential condensation and I2-mediated oxidative C–O/C–S bond formationA concise approach to polysubstituted oxazoles from N-acyl-2-bromo enamides via a copper(I)/amino acid-catalyzed intramolecular C-O bond formationDiscovery of an Orally Active and Liver-Targeted Prodrug of 5-Fluoro-2'-Deoxyuridine for the Treatment of Hepatocellular CarcinomaSynthesis of imidazo[1,5-a]pyridines via I2-mediated sp3 C-H aminationAnnulation Reactions of In-Situ-Generated N-(Het)aroyldiazenes with Isothiocyanates Leading to 2-Imino-1,3,4-oxadiazolinesThe role of chlorine atom on the binding between 2-phenyl-1H-benzimidazole analogues and fat mass and obesity-associated proteinSynthesis of phenanthridines by I2-mediated sp3 C-H aminationCardioprotection of (±)-sodium 5-bromo-2-(α-hydroxypentyl) benzoate (BZP) on mouse myocardium I/R injury through inhibiting 12/15-LOX-2 activityIodine-mediated oxidative N-N coupling of secondary amines to hydrazinesSynthesis of Functionalized Imidazolium Salts via Iodine-Mediated Annulations of EnaminesDesign, synthesis, and biological evaluation of novel 2'-deoxy-2'-fluoro-2'-C-methyl 8-azanebularine derivatives as potent anti-HBV agentsSynthesis of 2 H-Azirines via Iodine-Mediated Oxidative Cyclization of Enamines
P50
Q28485238-058ADC08-D017-4031-9E55-AF160CDD5CA9Q34478823-BE0EFADA-DDC4-4928-8604-DE0BA320A110Q35171063-18713D68-C83C-4FA6-A3B3-C0C6BFCF3A07Q38699932-162F003F-978C-42AB-9507-192A29AB9B78Q38735564-521B7906-F8E6-45DA-9235-388A7CA551C8Q38883214-84D45B0A-2212-40EF-A253-C308B93623EBQ38939226-274239F2-C50E-4A4B-ABC5-350053FB0C07Q39193434-BDF79709-4D79-4FC7-8BAC-94B32C345515Q39213344-C2C97969-0F46-409B-ABBE-0A2B4232A350Q39328622-82DB5584-55F3-433B-A989-A21B16B5B03DQ39617748-1523AF5F-DDCA-4DDA-A83D-1E36C92F874BQ40251429-338CD7E7-4B34-42F3-9754-8BF1EE6952DCQ41633135-97DE58A6-1114-414F-AC53-20C905DBE733Q42823608-0A54A1BF-5309-4080-944E-0D1C4BCD877AQ45324309-5198692D-2D29-4CBD-83EB-D04A1AF47570Q46687055-5FF03C10-1702-41E4-82C7-3A490C1A5D9EQ47315094-E7F5EC6A-9825-4596-96AD-5E054C0C062EQ47357645-0B3873BB-460C-4878-8D47-9A818911FDC9Q48156556-D83450A3-1575-45E6-9963-92D65FF6FD32Q48198845-B8759115-DD24-422F-979D-A08FA086B8D4Q50858609-D52EEB76-B42A-4006-9079-13606757ACDCQ51152404-91861D66-0265-4881-BEB4-38FA15C0064EQ51166933-27347614-59AE-4B6F-9485-70ADF2B81174Q51275356-5F4DC23B-EEB9-4D76-8A6B-6AEC4B1AF39EQ51494208-A182F4E1-EEC8-4F5F-9E14-39F18E2077ACQ53197855-15FB64B9-2E91-4FBD-A0D6-6A917E3C4E2BQ83777798-7DBC9742-E8CC-475B-9E36-9AF2E22D81A7Q85672627-45A07326-3209-4D3B-8FAC-39AB4738EC11Q86288642-E644A565-1930-4C19-A32A-3AD9E5EA0BE2Q87797637-7ACD58B9-4EE5-4537-A98B-BBE43EA717D3Q89078328-5EDBA53C-6C17-4A0D-9C26-7D78C917A8D2Q90433174-3E852BD3-8F55-405C-85F6-6B1E95ABF78BQ90472222-4AD54074-39F7-4AB0-9551-99B36FA9502BQ90690459-0D9C1D29-5157-4835-8607-361B46A2E3B3Q91952268-1157A5AD-F310-41DB-8801-7D133FEF6738Q92288124-A13A7C46-CB3A-4BD6-9ABE-D0ECB09567DFQ92438507-5F9F5573-081C-4E34-8B2B-EE2866944201Q92669850-AB958F47-9AD2-4DA5-876F-1FEDBE5F515EQ92951914-5FADE0AF-F590-41E4-9FB2-FB6F19D347CFQ93359023-F5B8A60A-0B51-49ED-840E-776723CDA97B
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Wenquan Yu
@ast
Wenquan Yu
@en
Wenquan Yu
@es
Wenquan Yu
@nl
Wenquan Yu
@sl
type
label
Wenquan Yu
@ast
Wenquan Yu
@en
Wenquan Yu
@es
Wenquan Yu
@nl
Wenquan Yu
@sl
prefLabel
Wenquan Yu
@ast
Wenquan Yu
@en
Wenquan Yu
@es
Wenquan Yu
@nl
Wenquan Yu
@sl
P106
P1153
36623063200
P31
P496
0000-0002-3711-0006