Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling.

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Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

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Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

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Item

label

Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

@en

Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

@nl

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Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

@en

Selective Irreversible Inhibit ...... ivity-Based Protein Profiling.

@nl

P1476

Selective Irreversible Inhibit ...... tivity-Based Protein Profiling

@en

P2093

Benjamin F Cravatt

http://www.w3.org/2001/XMLSchema#string

Radu M Suciu

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P2860

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

Notum deacylates Wnt proteins to suppress signalling activity

The pharmacological landscape and therapeutic potential of serine hydrolases

The Wnt signaling pathway in development and disease

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation

Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture

The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase

HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient

P304

563-568

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.8B00191

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Armand B Cognetta

Zachary Potter

P577

2018-05-26T00:00:00Z

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P698

29937983

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P932

6004566

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