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MALDI-TOF mass spectral analysis of siRNA degradation in serum confirms an RNAse A-like activity.Characterisation of the sarcomeric myosin heavy chain multigene family in the laboratory guinea pigBeta2-adrenergic agonist-induced hypertrophy of the quadriceps skeletal muscle does not modulate disease severity in the rodent meniscectomy model of osteoarthritis.IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesityResistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis.Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritisHypoxia modulates the phenotype of osteoblasts isolated from knee osteoarthritis patients, leading to undermineralized bone nodule formation.Characterisation of cell-penetrating peptide-mediated peptide deliveryThe hallmarks of osteoarthritis and the potential to develop personalised disease-modifying pharmacological therapeutics.Lung delivery studies using siRNA conjugated to TAT(48-60) and penetratin reveal peptide induced reduction in gene expression and induction of innate immunity.Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage.Creatine ingestion augments dietary carbohydrate mediated muscle glycogen supercompensation during the initial 24 h of recovery following prolonged exhaustive exercise in humans.11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.Bearings in Hip Arthroplasty: Joint Registries vs Precision Medicine: Review Article.Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle.Adolescent idiopathic scoliosis: evidence for intrinsic factors driving aetiology and progression.Povidone-Iodine Has a Profound Effect on In Vitro Osteoblast Proliferation and Metabolic Function and Inhibits Their Ability to Mineralize and Form Bone.Developing anti-inflammatory therapeutics for patients with osteoarthritis.Review: Long Noncoding RNAs in the Regulation of Inflammatory Pathways in Rheumatoid Arthritis and Osteoarthritis.The Effect of Vancomycin and Gentamicin Antibiotics on Human Osteoblast Proliferation, Metabolic Function, and Bone Mineralization.Suspended Manufacture of Biological Structures.Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis.IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development.Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass.The effect of the beta2-adrenoceptor agonist prodrug BRL-47672 on cardiovascular function, skeletal muscle myosin heavy chain, and MyoD expression in the rat.Catalog of Differentially Expressed Long Non-Coding RNA following Activation of Human and Mouse Innate Immune Response.Formulation and viscoelasticity of mineralised hydrogels for use in bone-cartilage interfacial reconstruction.Structuring of Hydrogels across Multiple Length Scales for Biomedical Applications.The role of microRNAs in glucocorticoid action.The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.The role of adipokines in skeletal muscle inflammation and insulin sensitivity.Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial FibroblastsThe commercial pig as a model of spontaneously-occurring osteoarthritisG protein-coupled receptor kinases 2 and 5 are differentially expressed in rat skeletal muscle and remain unchanged following beta2-agonist administrationFibre type-specific expression of p94, a skeletal muscle-specific calpainFibre type-specific expression of the calpain proteolytic system in skeletal muscleChronic treatment with the beta(2)-adrenoceptor agonist prodrug BRL-47672 impairs rat skeletal muscle function by inducing a comprehensive shift to a faster muscle phenotypeMatrix degradation in osteoarthritis primes the superficial region of cartilage for mechanical damageRegulation of the Inflammatory Synovial Fibroblast Phenotype by Metastasis-Associated Lung Adenocarcinoma Transcript 1 Long Noncoding RNA in Obese Patients With OsteoarthritisGeometric confinement is required for recovery and maintenance of chondrocyte phenotype in alginate
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P50
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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Simon W. Jones
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