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A global perspective on the influence of environmental exposures on the nervous systemEarly Childhood Diarrhea Predicts Cognitive Delays in Later Childhood Independently of Malnutrition.Prolonged maternal separation induces undernutrition and systemic inflammation with disrupted hippocampal development in mice.Early-life enteric infections: relation between chronic systemic inflammation and poor cognition in childrenGeography, population, demography, socioeconomic, anthropometry, and environmental status in the MAL-ED cohort and case-control study Sites in Fortaleza, Ceará, Brazil.Apolipoprotein E knockout mice have accentuated malnutrition with mucosal disruption and blunted insulin-like growth factor I responses to refeeding.Intestinal cell kinase is a novel participant in intestinal cell signaling responses to protein malnutrition.Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourished ratsRole of apolipoprotein E4 in protecting children against early childhood diarrhea outcomes and implications for later developmentEffects of glutamine alone or in combination with zinc and vitamin A on growth, intestinal barrier function, stress and satiety-related hormones in Brazilian shantytown children.Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished miceArginine decreases Cryptosporidium parvum infection in undernourished suckling mice involving nitric oxide synthase and arginase.Novel in vitro and in vivo models and potential new therapeutics to break the vicious cycle of Cryptosporidium infection and malnutrition.Zinc, vitamin A, and glutamine supplementation in Brazilian shantytown children at risk for diarrhea results in sex-specific improvements in verbal learningCryptosporidium-malnutrition interactions: mucosal disruption, cytokines, and TLR signaling in a weaned murine model.Evidence for genetic susceptibility to developing early childhood diarrhea among shantytown children living in northeastern Brazil.Alanyl-glutamine promotes intestinal epithelial cell homeostasis in vitro and in a murine model of weanling undernutritionApolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis.Apolipoprotein E4 influences growth and cognitive responses to micronutrient supplementation in shantytown children from northeast BrazilProlonged episodes of acute diarrhea reduce growth and increase risk of persistent diarrhea in children.Cryptosporidium infection causes undernutrition and, conversely, weanling undernutrition intensifies infection.Semantic fluency: a sensitive marker for cognitive impairment in children with heavy diarrhea burdens?Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.APOE4 protects the cognitive development in children with heavy diarrhea burdens in Northeast Brazil.Limitations in verbal fluency following heavy burdens of early childhood diarrhea in Brazilian shantytown children.Clostridium difficile toxin A induces intestinal epithelial cell apoptosis and damage: role of Gln and Ala-Gln in toxin A effects.Malnutrition as an enteric infectious disease with long-term effects on child developmentCaspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitroRole of retinol in protecting epithelial cell damage induced by Clostridium difficile toxin A.Infectious diseases, balanced polymorphisms, and human evolution: a declaration of interdependence.Treatment of Severe Refractory Hematuria due to Radiation-Induced Hemorrhagic Cystitis with Dexamethasone.Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents.Zinc and glutamine improve brain development in suckling mice subjected to early postnatal malnutrition.Glutamine and alanyl-glutamine promote crypt expansion and mTOR signaling in murine enteroids.Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient miceAlanyl-glutamine and glutamine supplementation improves 5-fluorouracil-induced intestinal epithelium damage in vitroIn vitro effect of antibiotics on biofilm formation by Bacteroides fragilis group strains isolated from intestinal microbiota of dogs and their antimicrobial susceptibility.Group a rotavirus and norovirus genotypes circulating in the northeastern Brazil in the post-monovalent vaccination era.Pharmacological, morphological and behavioral analysis of motor impairment in experimentally vitamin C deficient guinea pigs.Oral gabapentin treatment accentuates nerve and peripheral inflammatory responses following experimental nerve constriction in Wistar rats.
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wetenschapper
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հետազոտող
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Reinaldo B Oriá
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Reinaldo B Oriá
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Reinaldo B. Oriá
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Reinaldo B. Oriá
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Reinaldo B Oriá
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Reinaldo B Oriá
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Reinaldo B. Oriá
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Reinaldo B. Oriá
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Reinaldo B Oriá
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Reinaldo B Oriá
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Reinaldo B. Oriá
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Reinaldo B. Oriá
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6701746254
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0000-0002-6914-5481