about
Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes.Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers.Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond).Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal-Organic Frameworks.Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery.Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo.Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer.Dual-targeted polyplexes based on sequence-defined peptide-PEG-oligoamino amides.Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains.Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.Multifunctional Efficiency: Extending the Concept of Atom Economy to Functional Nanomaterials.Nanosized multifunctional polyplexes for receptor-mediated siRNA deliveryMultifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNASequence-defined nucleic acid carriers combining distinct modules for complexation, shielding, receptor-targeting and endosomal escapeEpidermal growth factor receptor targeted methotrexate and small interfering RNA co-deliveryCoordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the BiointerfaceMultifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown PotentialDelivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ulrich Lächelt
@ast
Ulrich Lächelt
@en
Ulrich Lächelt
@es
Ulrich Lächelt
@nl
Ulrich Lächelt
@sl
type
label
Ulrich Lächelt
@ast
Ulrich Lächelt
@en
Ulrich Lächelt
@es
Ulrich Lächelt
@nl
Ulrich Lächelt
@sl
prefLabel
Ulrich Lächelt
@ast
Ulrich Lächelt
@en
Ulrich Lächelt
@es
Ulrich Lächelt
@nl
Ulrich Lächelt
@sl
P106
P31
P496
0000-0002-4996-7592