about
Cardiolipin: characterization of distinct oxidized molecular speciesCEP biomarkers as potential tools for monitoring therapeuticsIdentification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen componentsPolyunsaturated phospholipids promote the oxidation and fragmentation of gamma-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipidsA 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA.Isolevuglandin-protein adducts in oxidized low density lipoprotein and human plasma: a strong connection with cardiovascular disease.The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophagesProtective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in miceDrusen proteome analysis: an approach to the etiology of age-related macular degeneration.Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.Isolevuglandins and mitochondrial enzymes in the retina: mass spectrometry detection of post-translational modification of sterol-metabolizing CYP27A1T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degenerationDiscovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipidsIsolevuglandin adducts in diseaseReceptor-Mediated Mechanism Controlling Tissue Levels of Bioactive Lipid Oxidation ProductsDistinguishing levuglandins produced through the cyclooxygenase and isoprostane pathways.High-resolution dynamic oxygen-17 MR imaging of mouse brain with golden-ratio-based radial sampling and k-space-weighted image reconstruction.Structural identification and cardiovascular activities of oxidized phospholipids.Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis.Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.Retinal pigment epithelium lipofuscin proteomics.Isolevuglandin-modified proteins, including elevated levels of inactive calpain-1, accumulate in glaucomatous trabecular meshworkNovel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE-/- mice and activate platelets via TLR2.Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeuticsCarboxyethylpyrrole adducts, age-related macular degeneration and neovascularization.Fragmentation of a linoleate-derived γ-hydroperoxy-α,β-unsaturated epoxide to γ-hydroxy- and γ-oxo-alkenals involves a unique pseudo-symmetrical diepoxycarbinyl radical.Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers.Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light.A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degenerationOxidative damage-induced inflammation initiates age-related macular degeneration.Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration.Formation of gamma-ketoaldehyde-protein adducts during ethanol-induced liver injury in mice.4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Induces Angiogenesis through Several Different Molecular Pathways.2-(ω-Carboxyethyl)pyrrole Antibody as a New Inhibitor of Tumor Angiogenesis and Growth.Metabolism of 4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone by Retinal Pigmented Epithelial Cells.4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) Lactone is a Biologically Active Precursor for the Generation of 2-(ω-Carboxyethyl)pyrrole (CEP) Derivatives of Proteins and Ethanolamine Phospholipids.Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate.Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Robert G Salomon
@nl
Robert G Salomon
@sl
Robert G. Salomon
@en
Robert G. Salomon
@es
type
label
Robert G Salomon
@nl
Robert G Salomon
@sl
Robert G. Salomon
@en
Robert G. Salomon
@es
prefLabel
Robert G Salomon
@nl
Robert G Salomon
@sl
Robert G. Salomon
@en
Robert G. Salomon
@es
P106
P1153
7101751271
P21
P31
P496
0000-0001-9456-3557