about
Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspasesComparative analysis of apoptosis and inflammation genes of mice and humansTid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survivalThe Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity.Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.Prognostic significance of apoptosis regulators in breast cancer.Expression of Bcl-2 family member Bid in normal and malignant tissues.Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responsesTNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice.Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancerAnti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphomaTNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic miceCADD, a Chlamydia protein that interacts with death receptors.Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines.Fludarabine Inhibits KV1.3 Currents in Human B Lymphocytes.Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines.T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic stateInduction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase.Differential requirements for tumor necrosis factor receptor-associated factor family proteins in CD40-mediated induction of NF-kappaB and Jun N-terminal kinase activation.Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.Granzyme release and caspase activation in activated human T-lymphocytes.Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.Bioconjugation through Mesitylene Thiol Alkylation.Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4-1BB).Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.Expression and function of alpha4/beta7 integrin on human natural killer cellsExpression of multiple apoptosis-regulatory genes in human breast cancer cell lines and primary tumorsA tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicityCD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFsMice Lacking bi-1 Gene Show Accelerated Liver RegenerationDysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in MiceTranslational regulation of the heat shock responseIntratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Juan M Zapata
@ast
Juan M Zapata
@en
Juan M Zapata
@es
Juan M Zapata
@nl
Juan M Zapata
@sl
type
label
Juan M Zapata
@ast
Juan M Zapata
@en
Juan M Zapata
@es
Juan M Zapata
@nl
Juan M Zapata
@sl
prefLabel
Juan M Zapata
@ast
Juan M Zapata
@en
Juan M Zapata
@es
Juan M Zapata
@nl
Juan M Zapata
@sl
P106
P21
P31
P496
0000-0002-0110-0009