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Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse ModelPlasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranesA novel 'gene insertion/marker out' (GIMO) method for transgene expression and gene complementation in rodent malaria parasitesTwo Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage developmentICAM-1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria modelAminoindoles, a novel scaffold with potent activity against Plasmodium falciparum.Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.The subcellular location of ovalbumin in Plasmodium berghei blood stages influences the magnitude of T-cell responses.CCR4-associated factor 1 coordinates the expression of Plasmodium falciparum egress and invasion proteins.Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria.Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria.Plasmodium products persist in the bone marrow and promote chronic bone loss.Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection.Generation of Transgenic Rodent Malaria Parasites Expressing Human Malaria Parasite Proteins.Deletion of the rodent malaria ortholog for falcipain-1 highlights differences between hepatic and blood stage merozoites.Hemozoin induces lung inflammation and correlates with malaria-associated acute respiratory distress syndrome.Screening inhibitors of P. berghei blood stages using bioluminescent reporter parasites.Genomic and transcriptomic comparisons of closely related malaria parasites differing in virulence and sequestration patternTranscriptomes of microglia in experimental cerebral malaria in mice in the presence and absence of Type I Interferon signalingRepeated clinical malaria episodes are associated with modification of the immune system in childrenComparison of whole blood and spleen transcriptional signatures over the course of an experimental malaria infectionTranscriptional profiling unveils type I and II interferon networks in blood and tissues across diseases
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jingwen Lin
@ast
Jingwen Lin
@en
Jingwen Lin
@es
Jingwen Lin
@nl
Jingwen Lin
@sl
type
label
Jingwen Lin
@ast
Jingwen Lin
@en
Jingwen Lin
@es
Jingwen Lin
@nl
Jingwen Lin
@sl
prefLabel
Jingwen Lin
@ast
Jingwen Lin
@en
Jingwen Lin
@es
Jingwen Lin
@nl
Jingwen Lin
@sl
P108
P106
P1153
55772458200
P31
P496
0000-0003-3338-8788