about
Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factorsGenome-wide analysis of mRNAs bound to the histone stem-loop binding proteinPhenome-Wide Association Studies: Embracing Complexity for DiscoveryConsistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) ConsortiumGenetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) studyEnabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) studyeMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variantsINTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.Uncovering the etiology of autism spectrum disorders: genomics, bioinformatics, environment, data collection and exploration, and future possibilities.Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.Methods of integrating data to uncover genotype-phenotype interactions.PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).PATTERNS IN BIOMEDICAL DATA-HOW DO WE FIND THEM?IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR.Molecular subsets in the gene expression signatures of scleroderma skin.A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum responseVisualizing genomic information across chromosomes with PhenoGramInvestigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studiesInterferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project BiobankLimited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury.Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis.Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) studyCharacterization of mitochondrial haplogroups in a large population-based sample from the United StatesPleiotropic genes for metabolic syndrome and inflammationPhenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass indexA phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.Knowledge-driven genomic interactions: an application in ovarian cancer.Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development.Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activityAntagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge.Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study dataLow frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data.Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex TraitsBiology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network.
P50
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P50
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P106
P1153
55571430100
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P2456
P31
P496
0000-0002-0565-6522