about
Platelets mediate cytotoxic T lymphocyte-induced liver damage.HBV pathogenesis in animal models: recent advances on the role of plateletsKupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitisAntiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirusTreatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic micePlatelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytesRapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.AAV6-mediated systemic shRNA delivery reverses disease in a mouse model of facioscapulohumeral muscular dystrophyA novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.Platelets promote liver immunopathology contributing to hepatitis B virus-mediated hepatocarcinogenesis.Chronic hepatitis B: role of anti-platelet therapy in inflammation control.Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.New players in non-alcoholic fatty liver disease induced carcinogenesis: lipid dysregulation impairs liver immune surveillance.Immunosurveillance of the liver by intravascular effector CD8(+) T cells.Bisphosphonates target B cells to enhance humoral immune responses.Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.Mother-to-child transmission of TT virus: sequence analysis of non-coding region of TT virus in infected mother-infant pairs.Acute self-limiting hepatitis C after possible sexual exposure: sequence analysis of the E-2 region of the infected patient and sexual partner.On the role of platelets in the pathogenesis of viral hepatitis.Bone marrow as an alternative site for islet transplantation.Ribavirin therapy for chronic hepatitis C does not modify HIV viral load in HIV-1 positive patients under antiretroviral treatment.Role of CCL2/MCP-1 in islet transplantation.Liver fibrosis in HIV-positive patients with hepatitis C virus: role of persistently normal alanine aminotransferase levels.In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.High mobility group box 1 orchestrates tissue regeneration via CXCR4.On the use of superparamagnetic hydroxyapatite nanoparticles as an agent for magnetic and nuclear in vivo imaging.Pathogenetic and antiviral immune responses against hepatitis B virus42. Correction of SCID-X1 by Targeted Genome Editing of Hematopoietic Stem/Progenitor Cells (HSPC) in the Mouse Model481. Targeted Genome Editing in Mouse Hematopoietic Stem/Progenitor Cells (HSPC) To Model Gene Correction of SCID-X1Towards personalized medicine in chronic HBV patients?The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver5 INVITED Role of haematopoietic cells in tumour angiogenesis: from discovery to targeted cancer gene therapyReduced severity of liver ischemia/reperfusion injury following hepatic resection in humans is associated with enhanced intrahepatic expression of Th2 cytokines
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Giovanni Sitia
@ast
Giovanni Sitia
@en
Giovanni Sitia
@es
Giovanni Sitia
@nl
type
label
Giovanni Sitia
@ast
Giovanni Sitia
@en
Giovanni Sitia
@es
Giovanni Sitia
@nl
prefLabel
Giovanni Sitia
@ast
Giovanni Sitia
@en
Giovanni Sitia
@es
Giovanni Sitia
@nl
P1053
K-1036-2016
P106
P1153
6602320571
P21
P31
P3829
P496
0000-0003-1024-9128