about
High-throughput screening (HTS) and hit validation to identify small molecule inhibitors with activity against NS3/4A proteases from multiple hepatitis C virus genotypesTime-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.Metabolism-directed structure optimization of benzimidazole-based Francisella tularensis enoyl-reductase (FabI) inhibitors.Proteasome inhibitors with pyrazole scaffolds from structure-based virtual screening.Interactions between human cytochrome P450 enzymes and steroids: physiological and pharmacological implications.Substrate-dependent modulation of the catalytic activity of CYP3A by erlotinibBioactivation of herbal constituents: simple alerts in the complex system.Interactions between phytochemicals from traditional Chinese medicines and human cytochrome P450 enzymes.Cycloartane triterpenoids from Cimicifuga yunnanensis induce apoptosis of breast cancer cells (MCF7) via p53-dependent mitochondrial signaling pathway.Examining the Uptake of Central Nervous System Drugs and Candidates across the Blood-Brain Barrier.Integrating in Silico and in Vitro Approaches To Predict Drug Accessibility to the Central Nervous System.Glycyrrhetinic acid exhibits strong inhibitory effects towards UDP-glucuronosyltransferase (UGT) 1A3 and 2B7.Inhibitory effects of curcumenol on human liver cytochrome P450 enzymes.Chiral Inhibition of Rivaroxaban Derivatives Towards UDP-Glucuronosyltransferase (UGT) Isoforms.Quantitative structure-retention relationship studies for taxanes including epimers and isomeric metabolites in ultra fast liquid chromatography.Rapid qualitative and quantitative determination of seven valuable taxanes from various Taxus species by UFLC-ESI-MS and UFLC-DAD.New insights for the risk of bisphenol A: inhibition of UDP-glucuronosyltransferases (UGTs).Inhibition behavior of fructus psoraleae's ingredients towards human carboxylesterase 1 (hCES1).Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis.Chemotaxonomic study of medicinal Taxus species with fingerprint and multivariate analysisProfiling of yew hair roots from various species using ultra-performance liquid chromatography/electrospray ionization mass spectrometryInhibitory potential of chlormadinone acetate (CMA) on five important UDP-glucuronosyltransferases in human liverReversible inhibition of four important human liver cytochrome P450 enzymes by diethylstilbestrolIdentification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb-drug interactionsStrong inhibition of deoxyschizandrin and schisantherin A toward UDP-glucuronosyltransferase (UGT) 1A3 indicating UGT inhibition-based herb–drug interactionChirality Influence of Zaltoprofen Towards UDP-Glucuronosyltransferases (UGTs) Inhibition Potential
P50
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P50
description
onderzoeker
@nl
researcher ORCID: 0000-0002-4229-1470
@en
name
Yan-Yan Zhang
@ast
Yan-Yan Zhang
@en
Yan-Yan Zhang
@es
Yan-Yan Zhang
@nl
type
label
Yan-Yan Zhang
@ast
Yan-Yan Zhang
@en
Yan-Yan Zhang
@es
Yan-Yan Zhang
@nl
prefLabel
Yan-Yan Zhang
@ast
Yan-Yan Zhang
@en
Yan-Yan Zhang
@es
Yan-Yan Zhang
@nl
P106
P1153
57189299279
P31
P496
0000-0002-4229-1470