about
The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPsTranslational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elementsA novel role for shuttling SR proteins in mRNA translationSLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and goutHomozygous SLC2A9 mutations cause severe renal hypouricemia.Viral and cellular mRNA-specific activators harness PABP and eIF4G to promote translation initiation downstream of cap bindingPoly(A)-binding proteins are required for diverse biological processes in metazoans.mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation.Direct stimulation of translation by the multifunctional herpesvirus ICP27 protein.Poly(A)-binding proteins and mRNA localization: who rules the roost?DAZAP1, an RNA-binding protein required for development and spermatogenesis, can regulate mRNA translation.Regulation of mRNA translation by 5'- and 3'-UTR-binding factors.The multifunctional poly(A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important role in co-ordinating its activities.Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.FMRP Associates with Cytoplasmic Granules at the Onset of Meiosis in the Human Oocyte.Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.Regulation of translation initiation by herpesviruses.Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation.Modulation of the cytoplasmic functions of mammalian post-transcriptional regulatory proteins by methylation and acetylation: a key layer of regulation waiting to be uncovered?Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs.A tail of translational regulation.Poly(A)-binding protein 1 partially relocalizes to the nucleus during herpes simplex virus type 1 infection in an ICP27-independent manner and does not inhibit virus replicationAn integrated model for the nucleo-cytoplasmic transport of cytoplasmic poly(A)-binding proteinsControl of translation initiation in animals.A molecular doorstop ensures a trickle through translational repression.Cleavage, a real turn-off? HIV-mediated proteolysis of PABP1.Gene expression in neuronal disease.Dazl binds in vivo to specific transcripts and can regulate the pre-meiotic translation of Mvh in germ cells.Cytoplasmic mRNA: move it, use it or lose it!IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4FRegulation of protein synthesis by mRNA structureRecombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switchTranslational control by repressor proteins binding to the 5'UTR of mRNAsmRNA-specific regulation of translation by poly(A)-binding proteins
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Nicola K Gray
@ast
Nicola K Gray
@en
Nicola K Gray
@es
Nicola K Gray
@nl
type
label
Nicola K Gray
@ast
Nicola K Gray
@en
Nicola K Gray
@es
Nicola K Gray
@nl
prefLabel
Nicola K Gray
@ast
Nicola K Gray
@en
Nicola K Gray
@es
Nicola K Gray
@nl
P106
P21
P31
P496
0000-0002-0413-1767