about
Oxidative DNA damage: mechanisms, mutation, and diseaseEuropean contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).Factors contributing to the outcome of oxidative damage to nucleic acids.Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA.Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.Biomarkers.Urinary 8-oxo-2'-deoxyguanosine: redox regulation of DNA repair in vivo?DNA repair: insights from urinary lesion analysis.Progress in the analysis of urinary oxidative DNA damage.Novel method for the high-throughput processing of slides for the comet assay.Oxidative DNA damage and disease: induction, repair and significance.8-Oxo-deoxyguanosine: reduce, reuse, recycle?Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma.Rapid measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometryNucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine.Does measurement of oxidative damage to DNA have clinical significance?Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine.Measurement and meaning of oxidatively modified DNA lesions in urine.Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.Concurrent beneficial (vitamin D production) and hazardous (cutaneous DNA damage) impact of repeated low-level summer sunlight exposures.Harmonising measurements of 8-oxo-7,8-dihydro-2'-deoxyguanosine in cellular DNA and urine.Immunochemical detection of UV-induced DNA damage and repair.Simplified method for the collection, storage, and comet assay analysis of DNA damage in whole blood.Inter-laboratory variation in DNA damage using a standard comet assay protocol.Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine analysis by an improved ELISA: An inter-laboratory comparison study.Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells.Antiserum detection of reactive carbonyl species-modified DNA in human colonocytes.17 beta-Oestradiol attenuates nucleotide excision repair.Monoclonal antibody to single-stranded DNA: a potential tool for DNA repair studies.Recommendations for standardized description of and nomenclature concerning oxidatively damaged nucleobases in DNA.Gene expression profiling reveals new protective roles for vitamin C in human skin cells.DNA repair and the origins of urinary oxidized 2'-deoxyribonucleosides.Caffeine intake during pregnancy, late miscarriage and stillbirth.DNA nucleotide excision repair, where do all the cyclobutane pyrimidine dimers go?Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA.Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.Combination of azathioprine and UVA irradiation is a major source of cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine.
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հետազոտող
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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Marcus S Cooke
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