about
Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonistsSynthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiopheneDesign, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonistsNew 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists.DNA minor groove binders as potential antitumor and antimicrobial agents.Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.Recent improvements in the development of A(2B) adenosine receptor agonists.Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering.Activation of TRPA1 on dural afferents: a potential mechanism of headache pain.Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agentsOzone-Induced Hypertussive Responses in Rabbits and Guinea Pigs.Synthesis and biological evaluation of 2-aroyl-4-phenyl-5-hydroxybenzofurans as a new class of antitubulin agents.Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents.Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications.TRP channels as therapeutic targets in airway disorders: a patent review.History and perspectives of A2A adenosine receptor antagonists as potential therapeutic agents.Transient receptor potential ankyrin 1 (TRPA1) antagonists.Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.Design, synthesis, and biological evaluation of thiophene analogues of chalcones.Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors.Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles.Recent developments in the field of A2A and A3 adenosine receptor antagonists.The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.The blockade of transient receptor potential ankirin 1 (TRPA1) signalling mediates antidepressant- and anxiolytic-like actions in mice.New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.Adenosine modulates HIF-1{alpha}, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells.alpha-Bromoacrylamido N-substituted isatin derivatives as potent inducers of apoptosis in human myeloid leukemia cells.Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A₁ adenosine receptor.Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists.
P50
Q28184705-124CE80B-1A5F-47BF-A8C2-CF260C039D15Q28247159-AAE0E573-670B-4DF5-9444-37893F662AA7Q28248114-30062299-6AAE-4233-B986-11D98FC1E7A5Q28260888-08B696A1-1888-4AD8-93A9-CDC264C8499BQ30995497-7F73CD53-1A9C-4964-8445-6175F044378BQ33203300-7829991D-07D3-4A98-89CF-B618412742D6Q34107652-0ED78CA7-77E5-41E8-9E0F-7E0D1DF1EBBDQ34156232-64D47FCC-352E-4CF9-8186-EEC1E27F4975Q34222859-0E0AB21D-9180-48B6-9147-0F9049747F0DQ34228530-B0479C54-171B-43BB-B83A-B1E4299BC0BDQ34774668-98ED9FE2-9B4D-4547-8525-777394EA4913Q35694476-D3F445AF-F89B-438A-AE25-070229708E51Q36079759-09D789F5-8001-41BA-9795-BF846723C953Q36146803-C5FD08DB-0B25-4C9C-8ECC-2E6F6168FBE2Q36146946-0305C91A-293D-4D84-98C3-BA1186CE2E71Q36503104-9DF9774E-9610-43B8-A19D-DB1213DD72ADQ36822993-AE3ADD0C-B712-487F-A79F-18508C90E971Q37160063-BE620D07-3BC9-46BC-940D-1692D4630E1FQ37317311-C63E3C2B-317D-4A49-AE48-9714A754EB68Q37481245-3AD0099F-6F46-420E-B4F7-BD15F99FC474Q37507733-A1851779-B8DE-4F0A-A9DA-AEAA0FDB1A9BQ37999065-7548D139-863C-4C82-9C64-5AC153047F85Q38016197-79F05E05-93A3-4849-8C75-0B36D5642D04Q38395423-0A12D218-3CE7-497C-9660-644CC221D85FQ38411474-5158F478-665C-4FBF-BEBC-5B528ED03C87Q39665934-04792C3D-7D8B-4C60-A4AC-FDAE65EC9A68Q39987814-CE14D8EB-4653-4037-9687-833B33A2148FQ40015194-3CC53DB1-BDDC-4281-9FDB-05FFEEE6A257Q40221429-3D1EA4F5-8140-4107-BB6F-0FD8F34A0DE4Q40264626-20A1C38C-2997-4B61-B2B3-A4CB8CFE8E18Q40399911-C796442E-0541-472F-8552-94B8D1E36C45Q40647461-F39ACD8D-3EF7-47E3-95C1-29B167691281Q41374415-C4650FEC-8D99-49B9-8453-5BB5B8A34B60Q41865064-24DC5C4E-3B68-42F2-BAC2-F0CC97BFE5D4Q42732271-5C61444F-D130-4EB9-9C59-B73988A983E3Q42743261-D42DD825-96D7-411F-A10E-4739934AAB7BQ43260470-EB45A0F1-5D05-45EC-A418-FD24DE4A2952Q43294280-361C9D53-2E58-4EFF-AE51-943F2948D8E5Q44013005-23B8DC55-E4BA-40DE-8729-A2865FD764BDQ44210643-ABF35B8C-890F-41F7-AD84-97B9574B40E6
P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Delia Preti
@ast
Delia Preti
@en
Delia Preti
@es
Delia Preti
@nl
type
label
Delia Preti
@ast
Delia Preti
@en
Delia Preti
@es
Delia Preti
@nl
prefLabel
Delia Preti
@ast
Delia Preti
@en
Delia Preti
@es
Delia Preti
@nl
P1053
G-9916-2015
P106
P21
P31
P3829
P496
0000-0002-1075-3781