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Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune ResponseBalancing the immune response in the brain: IL-10 and its regulationA method for the generation of ectromelia virus (ECTV) recombinants: in vivo analysis of ECTV vCD30 deletion mutants.CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses.Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis.The C allele of rs5743836 polymorphism in the human TLR9 promoter links IL-6 and TLR9 up-regulation and confers increased B-cell proliferationType I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages.Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression.Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection.A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus.TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose.P. brasiliensis virulence is affected by SconC, the negative regulator of inorganic sulfur assimilation.Analysis of a local HIV-1 epidemic in portugal highlights established transmission of non-B and non-G subtypesMyeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infectionIL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages.A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis.Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophagesInhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus.Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity.Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiationTPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN productionDifferential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages.The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphomaType I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling.Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages.The regulation of IL-10 expression.Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages.Genetic variability of immunomodulatory genes in ectromelia virus isolates detected by denaturing high-performance liquid chromatography.Experimental study of tuberculosis: From animal models to complex cell systems and organoids.IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity.BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4⁺IL-17⁺TNF⁺IL-2⁺ T cells.TLR2 deficiency by compromising p19 (IL-23) expression limits Th 17 cell responses to Mycobacterium tuberculosis.The Troika Host-Pathogen-Extrinsic Factors in Tuberculosis: Modulating Inflammation and Clinical Outcomes.Evidence for diversifying selection in a set of Mycobacterium tuberculosis genes in response to antibiotic- and nonantibiotic-related pressure.Interferon-β regulates the production of IL-10 by toll-like receptor-activated microglia.The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis.GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4+ T cells.Identification of a macrophage-specific chromatin signature in the IL-10 locus.
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P50
description
hulumtuese
@sq
researcher
@en
հետազոտող
@hy
name
Margarida Saraiva
@ast
Margarida Saraiva
@en
Margarida Saraiva
@es
Margarida Saraiva
@nl
type
label
Margarida Saraiva
@ast
Margarida Saraiva
@en
Margarida Saraiva
@es
Margarida Saraiva
@nl
prefLabel
Margarida Saraiva
@ast
Margarida Saraiva
@en
Margarida Saraiva
@es
Margarida Saraiva
@nl
P106
P1153
35079223500
P21
P31
P496
0000-0002-8180-1293