about
Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.Transcriptome analysis identifies TNF superfamily receptors as potential therapeutic targets in alcoholic hepatitis.CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitisCulture of mouse embryonic stem cells with serum but without exogenous growth factors is sufficient to generate functional hepatocyte-like cells.Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cellsThe biliary epithelium gives rise to liver progenitor cellsResistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cellsIntegrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate CellsChemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis.Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesisIn vitro reversion of activated primary human hepatic stellate cellsGas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis.Liver fibrogenesis: a new role for the renin-angiotensin system.Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cellsLPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic HepatitisStem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis CHuman and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.Fermented milk containing Lactobacillus paracasei subsp. paracasei CNCM I-1518 reduces bacterial translocation in rats treated with carbon tetrachloride.Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients.Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors.Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation.Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells.Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis.Pentraxin-3 modulates lipopolysaccharide-induced inflammatory response and attenuates liver injury.Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication.Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes.Differentiation of rat multipotent adult progenitor cells to functional hepatocyte-like cells by mimicking embryonic liver development.Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans.Human hepatic stellate cells secrete adrenomedullin: potential autocrine factor in the regulation of cell contractility.Atorvastatin attenuates angiotensin II-induced inflammatory actions in the liver.Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury.A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury.Expression of microRNA-155 in inflammatory cells modulates liver injury.Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression.Mesenchymal stromal cells for immunomodulatory cell therapy in liver transplantation: One step at a time.A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.Targeting the renin-angiotensin system in liver fibrosis.
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P50
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wetenschapper
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P Sancho-Bru
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P1053
D-4900-2014
P106
P31
P496
0000-0001-5569-9259