about
Structural changes and proapoptotic peroxidase activity of cardiolipin-bound mitochondrial cytochrome cHydrophobic mismatch between helices and lipid bilayers.High-Field Dynamic Nuclear Polarization for Solid and Solution Biological NMRMAS (1)H NMR Probes Freezing Point Depression of Water and Liquid-Gel Phase Transitions in LiposomesLipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1.Dynamic nuclear polarization of amyloidogenic peptide nanocrystals: GNNQQNY, a core segment of the yeast prion protein Sup35p.Solid-state NMR study of amyloid nanocrystals and fibrils formed by the peptide GNNQQNY from yeast prion protein Sup35p.Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine coreHigh-resolution solid-state NMR structure of alanyl-prolyl-glycine.Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance.Amyloid-like fibrils from a domain-swapping protein feature a parallel, in-register conformation without native-like interactions.Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine coreObservation of a low-temperature, dynamically driven structural transition in a polypeptide by solid-state NMR spectroscopy.Peptide-Directed Assembly of Single-Helical Gold Nanoparticle Superstructures Exhibiting Intense Chiroptical Activity.How amyloid precursor protein protects itself from cleavage.Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation.Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties.β-hairpin-mediated nucleation of polyglutamine amyloid formation.D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells.Domain swapping and amyloid fibril conformation.Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides.Structural characterization of the caveolin scaffolding domain in association with cholesterol-rich membranes.Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins.Lipid dependence of membrane anchoring properties and snorkeling behavior of aromatic and charged residues in transmembrane peptides.Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations.Energetics Underlying Twist Polymorphisms in Amyloid Fibrils.In support of the BMRB.Insights into protein misfolding and aggregation enabled by solid-state NMR spectroscopy.On the use of ultracentrifugal devices for routine sample preparation in biomolecular magic-angle-spinning NMR.Methionine oxidized apolipoprotein A-I at the crossroads of HDL biogenesis and amyloid formation.Hidden motions and motion-induced invisibility: Dynamics-based spectral editing in solid-state NMR.New applications of solid-state NMR in structural biologyMultipole-multimode Floquet theory of rotational resonance width experiments: 13C-13C distance measurements in uniformly labeled solidsTryptophan-Anchored Transmembrane Peptides Promote Formation of Nonlamellar Phases in Phosphatidylethanolamine Model Membranes in a Mismatch-Dependent Manner†Structural Fingerprinting of Protein Aggregates by Dynamic Nuclear Polarization-Enhanced Solid-State NMR at Natural Isotopic AbundanceComplexes obtained by electrophilic attack on a dinitrogen-derived terminal molybdenum nitride: electronic structure analysis by solid state CP/MAS 15N NMR in combination with DFT calculationsSurface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized DynamicsConformational studies of pathogenic expanded polyglutamine protein deposits from Huntington's disease
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Patrick van der Wel
@ast
Patrick van der Wel
@en
Patrick van der Wel
@es
Patrick van der Wel
@nl
type
label
Patrick van der Wel
@ast
Patrick van der Wel
@en
Patrick van der Wel
@es
Patrick van der Wel
@nl
altLabel
P. van der Wel
@nl
prefLabel
Patrick van der Wel
@ast
Patrick van der Wel
@en
Patrick van der Wel
@es
Patrick van der Wel
@nl
P106
P1153
6701610354
P31
P496
0000-0002-5390-3321
P735
P7449
PRS1340238