about
Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleosideDisaccharide nucleosides and oligonucleotides on their basis. New tools for the study of enzymes of nucleic acid metabolism.A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicityDNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction- modification enzymes.Affinity modification of EcoRII DNA methyltransferase by the dialdehyde-substituted DNA duplexes: mapping the enzyme region that interacts with DNA.Disaccharide pyrimidine nucleosides and their derivatives: a novel group of cell-penetrating inhibitors of poly(ADP-ribose) polymerase 1.Fluorination of Naturally Occurring N⁶-Benzyladenosine Remarkably Increased Its Antiviral Activity and Selectivity.Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine.Incorporation of a disaccharide nucleoside into the backbone of double-stranded DNA: crystallization and preliminary X-ray diffraction.Chemical modification of the plant isoprenoid cytokinin N(6)-isopentenyladenosine yields a selective inhibitor of human enterovirus 71 replication.A route to 2',5'-oligoadenylates with increased stability towards phosphodiesterases.2'-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides.Oligodeoxynucleotides containing N1-methyl-2'-deoxyadenosine and N6-methyl-2'-deoxyadenosine.Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue.A comparative study on the cleavage of stereoisomeric uridylyl(3',5')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts.Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine.Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate.Chemical incorporation of 1-methyladenosine, minor tRNA component, into oligonucleotides.Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis.Detection of RNA hybridization by pyrene-labeled probes.Substrate specificity of thymidine phosphorylase of E. coli: role of hydroxyl groups.Chemoenzymatic synthesis of cytokinins from nucleosides: ribose as a blocking group.Substrate specificity of Escherichia coli thymidine phosphorylase.N⁶-(benzyloxymethyl)adenosine is a novel anticytokinin, an antagonist of cytokinin receptor CRE1/AHK4 of Arabidopsis.Synthesis of RNA ContainingO-β-D-Ribofuranosyl-(1″2′)-adenosine-5″-phosphate and 1-Methyladenosine, Minor Components of tRNAOligonucleotides Containing Disaccharide Nucleosides: Synthesis, Physicochemical, and Substrate PropertiesMapping of T7 RNA polymerase active site with novel reagents - oligonucleotides with reactive dialdehyde groupsNovel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapySubstrate properties of C'-methyl UTP derivatives in T7 RNA polymerase reactions. Evidence for N-type NTP conformationDetermination of the nucleotide conformation in the productive enzyme-substrate complexes of RNA-depolymerasesSolid-supported 2'-O-glycoconjugation of oligonucleotides by azidation and click reactionsFacile synthesis of 8-azido-6-benzylaminopurinePhysicochemical characterization of uridine phosphorylase from Shewanella oneidensis MR-1Strained Conformations of Nucleosides in Active Sites of Nucleoside PhosphorylasesDistinct Peculiarities of In Planta Synthesis of Isoprenoid and Aromatic Cytokinins
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Sergei Nikolajewitsch Michailow
@de
Sergey Mikhailov
@ast
Sergey Mikhailov
@en
Sergey Mikhailov
@es
Sergey Mikhailov
@nl
Сергей Николаевич Михайлов
@ru
type
label
Sergei Nikolajewitsch Michailow
@de
Sergey Mikhailov
@ast
Sergey Mikhailov
@en
Sergey Mikhailov
@es
Sergey Mikhailov
@nl
Сергей Николаевич Михайлов
@ru
altLabel
Sergei Michailow
@de
Sergey Mikhaylov
@en
Sergey Nikolayevich Mikhaylov
@en
prefLabel
Sergei Nikolajewitsch Michailow
@de
Sergey Mikhailov
@ast
Sergey Mikhailov
@en
Sergey Mikhailov
@es
Sergey Mikhailov
@nl
Сергей Николаевич Михайлов
@ru
P106
P1153
35446561200
P21
P31
P496
0000-0002-1363-9706