about
Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence codep53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening systemQuantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional AssayDominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.Identification of new p53 target microRNAs by bioinformatics and functional analysisWhole-genome cartography of p53 response elements ranked on transactivation potential.Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-moleculeRole of the non-neuronal human cholinergic system in lung cancer and mesothelioma: possibility of new therapeutic strategies.Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements.Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent.The Immunoregulatory Potential of Particle Radiation in Cancer Therapy.TP53 mutants in the tower of babel of cancer progression.The 5'-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding.p53-directed translational control can shape and expand the universe of p53 target genes.The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma.Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development.Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction.
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alessandra Bisio
@ast
Alessandra Bisio
@en
Alessandra Bisio
@es
Alessandra Bisio
@nl
type
label
Alessandra Bisio
@ast
Alessandra Bisio
@en
Alessandra Bisio
@es
Alessandra Bisio
@nl
prefLabel
Alessandra Bisio
@ast
Alessandra Bisio
@en
Alessandra Bisio
@es
Alessandra Bisio
@nl
P106
P1153
57191905799
P21
P31
P496
0000-0002-3326-1923