about
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vesselsTargeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisRole of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesisTargeted deletion of the cytosolic domain of tissue factor in mice does not affect developmentMice lacking factor VII develop normally but suffer fatal perinatal bleedingImpaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degenerationAbnormal blood vessel development and lethality in embryos lacking a single VEGF alleleMembrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.Bevacizumab revisited: its use in different mouse models of ocular pathologies.Ocular hypertension results in retinotopic alterations in the visual cortex of adult mice.The effect of AMA0428, a novel and potent ROCK inhibitor, in a model of neovascular age-related macular degeneration.The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization.Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo.αB-Crystallin regulates expansion of CD11b⁺Gr-1⁺ immature myeloid cells during tumor progression.ROCK inhibition as a novel potential strategy for axonal regeneration in optic neuropathiesComplementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration.MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment.Inhibition of placental growth factor improves surgical outcome of glaucoma surgery.Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis.Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System.Matrix metalloproteinase-3 in the central nervous system: a look on the bright side.MMPs in the trabecular meshwork: promising targets for future glaucoma therapies?MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair?Improving patient outcomes following glaucoma surgery: state of the art and future perspectives.Towards axonal regeneration and neuroprotection in glaucoma: Rho kinase inhibitors as promising therapeutics.Rho kinase inhibitor AMA0526 improves surgical outcome in a rabbit model of glaucoma filtration surgery.Modulation of wound healing in glaucoma surgery.Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.Matrix metalloproteinases as promising regulators of axonal regrowth in the injured adult zebrafish retinotectal system.Amyloid β Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases.Decreased thyroid hormone signaling accelerates the reinnervation of the optic tectum following optic nerve crush in adult zebrafish.Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.Characterizing microglia activation: a spatial statistics approach to maximize information extraction.Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase.VEGF-D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis.Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.Toxicology studies with recombinant staphylokinase and with SY 161-P5, a polyethylene glycol-derivatized cysteine-substitution mutant.Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.
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forsker
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wetenschapper
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հետազոտող
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L. Moons
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L. Moons
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Lieve Moons
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Lieve Moons
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L. Moons
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P106
P1153
7003340749
P31
P496
0000-0003-0186-1411