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Are cysteinyl leukotrienes involved in allergic responses in human skin?Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survivalCaveolae protect endothelial cells from membrane rupture during increased cardiac outputDietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils.Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils.Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism.The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion.Cutaneous exposure to hypoxia does not affect skin perfusion in humans.Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity.Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil functionHIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.HIF2α-arginase axis is essential for the development of pulmonary hypertension.HIF isoforms in the skin differentially regulate systemic arterial pressure.Advances in neutrophil biology: clinical implications.Epidermal deletion of HIF-2α stimulates wound closure.Evasion of Neutrophil Extracellular Traps by Respiratory PathogensHypoxia causes IL-8 secretion, Charcot Leyden crystal formation, and suppression of corticosteroid-induced apoptosis in human eosinophils.Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome.Cardiovascular adaptation to hypoxia and the role of peripheral resistanceCystic fibrosis neutrophils have normal intrinsic reactive oxygen species generation.Role of PI3-kinase-dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival.Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis.Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants.The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release.Effect of priming on activation and localization of phospholipase D-1 in human neutrophils.z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species.Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance.Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils.Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils.Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells.The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia.Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosisInterleukin-5 inhibits glucocorticoid-mediated apoptosis in human eosinophilsProlonged survival of neutrophils from patients with F508 CFTR mutationsEating their way out of trouble: selective uptake of apoptotic eosinophils by bronchial epithelial cellsProfound overexpression of leukotriene C4 synthase in bronchial biopsies from aspirin-intolerant asthmatic patients
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Andrew S Cowburn
@ast
Andrew S Cowburn
@en
Andrew S Cowburn
@es
Andrew S Cowburn
@nl
type
label
Andrew S Cowburn
@ast
Andrew S Cowburn
@en
Andrew S Cowburn
@es
Andrew S Cowburn
@nl
prefLabel
Andrew S Cowburn
@ast
Andrew S Cowburn
@en
Andrew S Cowburn
@es
Andrew S Cowburn
@nl
P106
P1153
6603656988
P31
P496
0000-0001-9145-4275