Laboratory evolution of enantiocomplementary Candida antarctica lipase B mutants with broad substrate scope
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Tuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot SpotCombining a Clostridial enzyme exhibiting unusual active site plasticity with a remarkably facile sigmatropic rearrangement: rapid, stereocontrolled entry into densely functionalized fluorinated phosphonates for chemical biologyA smart library of epoxide hydrolase variants and the top hits for synthesis of (S)-β-blocker precursors.Improvement of biocatalysts for industrial and environmental purposes by saturation mutagenesisExploring the enantioselective mechanism of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by iterative saturation mutagenesisCharacterization of a recombinant (+)-γ-lactamase from Microbacterium hydrocarbonoxydans which provides evidence that two enantiocomplementary γ-lactamases are in the strain.Engineering a thermostable fungal GH10 xylanase, importance of N-terminal amino acids.Combinatorial library based engineering of Candida antarctica lipase A for enantioselective transacylation of sec-alcohols in organic solvent.Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus.Chemical reactions directed Peptide self-assembly.Directed Evolution of Enzymes for Industrial Biocatalysis.Increasing the activity and enantioselectivity of lipases by sol-gel immobilization: further advancements of practical interest.Recent advances in engineering proteins for biocatalysis.Chemoenzymatic dynamic kinetic resolution: a powerful tool for the preparation of enantiomerically pure alcohols and amines.Gram-Scale Synthesis of Chiral Cyclopropane-Containing Drugs and Drug Precursors with Engineered Myoglobin Catalysts Featuring Complementary Stereoselectivity.Synthetically useful variants of industrial lipases from Burkholderia cepacia and Pseudomonas fluorescens.Exploring water as building bricks in enzyme engineering.Immobilization of Candida antarctic Lipase B on Functionalized Ionic Liquid Modified MWNTs.Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform.Rational design of esterase BioH with enhanced enantioselectivity towards methyl (S)-o-chloromandelate.Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.Two Enzyme Cooperatively Catalyzed Tandem Polymerization for the Synthesis of Polyester Containing Chiral (R)- or (S)-Ibuprofen Pendants
P2860
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P2860
Laboratory evolution of enantiocomplementary Candida antarctica lipase B mutants with broad substrate scope
description
im Februar 2013 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
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наукова стаття, опублікована в лютому 2013
@uk
name
Laboratory evolution of enanti ...... nts with broad substrate scope
@en
Laboratory evolution of enanti ...... nts with broad substrate scope
@nl
type
label
Laboratory evolution of enanti ...... nts with broad substrate scope
@en
Laboratory evolution of enanti ...... nts with broad substrate scope
@nl
prefLabel
Laboratory evolution of enanti ...... nts with broad substrate scope
@en
Laboratory evolution of enanti ...... nts with broad substrate scope
@nl
P2093
P356
P1476
Laboratory evolution of enanti ...... nts with broad substrate scope
@en
P2093
Manfred T Reetz
Pankaj Soni
P304
P356
10.1021/JA310455T
P407
P577
2013-02-06T00:00:00Z