Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 co-stimulatory pathway: requirement for both B7-1 and B7-2
about
Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cellsCell-cell interactions in synovitis: antigen presenting cells and T cell interaction in rheumatoid arthritis.Vstm3 is a member of the CD28 family and an important modulator of T-cell functionCD86 is an activation receptor for NK cell cytotoxicity against tumor cellsCTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris.CD28-B7 blockade prevents the development of experimental autoimmune glomerulonephritis.Future prospects for anti-cytokine treatment.The genetic and immunopathological processes underlying collagen-induced arthritis.Abatacept: the evidence for its place in the treatment of rheumatoid arthritis.Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig.Cell therapy for autoimmune diseases: does it have a future?Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?Targeting the B7 family of co-stimulatory molecules: successes and challenges.Co-stimulatory and Co-inhibitory Pathways in Autoimmunity.Abatacept in difficult-to-treat juvenile idiopathic arthritis.Pharmacotherapy: concepts of pathogenesis and emerging treatments. Co-stimulation and T cells as therapeutic targets.B effector cells in rheumatoid arthritis and experimental arthritis.Coinhibitory molecules in autoimmune diseases.Challenges and opportunities in targeting the CD28/CTLA-4 pathway in transplantation and autoimmunity.Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway.Therapeutic effects of antibodies to tumor necrosis factor-alpha, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis.Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care.CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis.Abatacept in the treatment of rheumatoid arthritis.Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach.Antibody-based targeted delivery of interleukin-4 synergizes with dexamethasone for the reduction of inflammation in arthritis.Engagement of the CD137 (4-1BB) costimulatory molecule inhibits and reverses the autoimmune process in collagen-induced arthritis and establishes lasting disease resistance.Influence of CD4 or CD8 deficiency on collagen-induced arthritis
P2860
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P2860
Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 co-stimulatory pathway: requirement for both B7-1 and B7-2
description
im Oktober 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 October 1996
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 1996
@uk
name
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@en
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@nl
type
label
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@en
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@nl
prefLabel
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@en
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@nl
P356
P1476
Prevention and amelioration of ...... irement for both B7-1 and B7-2
@en
P2093
M Feldmann
M J Walmsley
P304
P356
10.1002/EJI.1830261008
P407
P577
1996-10-01T00:00:00Z