about
Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivoSystematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data.A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.Placental mesenchymal stromal cells derived from blood vessels or avascular tissues: what is the better choice to support endothelial cell function?Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation.Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.Isolation and large scale expansion of adult human endothelial colony forming progenitor cells.A robust potency assay highlights significant donor variation of human mesenchymal stem/progenitor cell immune modulatory capacity and extended radio-resistance.Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.Pro-angiogenic induction of myeloid cells for therapeutic angiogenesis can induce mitogen-activated protein kinase p38-dependent foam cell formation.Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells.Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions.Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML.Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.Platelet-derived growth factors for GMP-compliant propagation of mesenchymal stromal cells.Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum.Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells.Positive contrast of SPIO-labeled cells by off-resonant reconstruction of 3D radial half-echo bSSFP.Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue.Mesenchymal stromal cells from the human placenta promote neovascularization in a mouse model in vivo.Humanized system to propagate cord blood-derived multipotent mesenchymal stromal cells for clinical application.Thiolated polyacrylic acid-modified iron oxide nanoparticles forin vitrolabeling and MRI of stem cellsCorrection: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6Immune cells mimic the morphology of endothelial progenitor colonies in vitroEndothelial colony-forming progenitor cell isolation and expansionTP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse modelIncreased Expression of Micro-RNA-23a Mediates Chemoresistance to Cytarabine in Acute Myeloid Leukemia
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Andreas Reinisch
@ast
Andreas Reinisch
@en
Andreas Reinisch
@es
Andreas Reinisch
@nl
type
label
Andreas Reinisch
@ast
Andreas Reinisch
@en
Andreas Reinisch
@es
Andreas Reinisch
@nl
prefLabel
Andreas Reinisch
@ast
Andreas Reinisch
@en
Andreas Reinisch
@es
Andreas Reinisch
@nl
P106
P31
P496
0000-0001-9333-7689