about
TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasisCell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activationHalofuginone inhibits the establishment and progression of melanoma bone metastases.TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastasesGLI2-mediated melanoma invasion and metastasis.Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo.Overlapping activities of TGF-β and Hedgehog signaling in cancer: therapeutic targets for cancer treatment.Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.Crosstalk between TGF-β and hedgehog signaling in cancer.GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells.JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing.Systematic classification of melanoma cells by phenotype-specific gene expression mapping.Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio.Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.[Transforming growth factor-betas: smad signaling and roles in physiopathology]Inhibition of constitutive NF-kappa B activity suppresses tumorigenicity of Ewing sarcoma EW7 cells.Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone MetastasisNF-κB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFα-treated Ewing sarcoma cellsInduction of p21Waf1/Cip1 by TNFα requires NF-κB activity and antagonizes apoptosis in Ewing tumor cellsNF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Delphine Javelaud
@ast
Delphine Javelaud
@en
Delphine Javelaud
@es
Delphine Javelaud
@nl
type
label
Delphine Javelaud
@ast
Delphine Javelaud
@en
Delphine Javelaud
@es
Delphine Javelaud
@nl
prefLabel
Delphine Javelaud
@ast
Delphine Javelaud
@en
Delphine Javelaud
@es
Delphine Javelaud
@nl
P106
P1153
6603228905
P31
P496
0000-0002-7674-7739