about
OASIS: online application for the survival analysis of lifespan assays performed in aging research3-D worm tracker for freely moving C. elegansC. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation.The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signalingGenes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegansThe role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterLifespan extension by conditions that inhibit translation in Caenorhabditis elegansDissection of C. elegans behavioral genetics in 3-D environments.Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans.A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes.Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression.Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans.Beta-lapachone, a modulator of NAD metabolism, prevents health declines in aged mice.Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activityRNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegansTissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegansMitochondria and organismal longevity.Regulation of lifespan by chemosensory and thermosensory systems: findings in invertebrates and their implications in mammalian aging.SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fatInhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegansRNA helicase SACY-1 is required for longevity caused by various genetic perturbations in Caenorhabditis elegans.A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila.Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.Meeting Report: International Symposium on the Genetics of Aging and Life History II.Myricetin improves endurance capacity and mitochondrial density by activating SIRT1 and PGC-1αMultiplex quantitative analysis of microRNA expression via exponential isothermal amplification and conformation-sensitive DNA separationLight adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin.Suppression of constant-light-induced blindness but not retinal degeneration by inhibition of the rhodopsin degradation pathway.Precise expression profiling by stuffer-free multiplex ligation-dependent probe amplification.Light-dependent translocation of visual arrestin regulated by the NINAC myosin III.RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan.Mitochondrial chaperone HSP-60 regulates anti-bacterial immunity via p38 MAP kinase signaling.Western Blot Analysis of C. elegans Proteins.Mitochondria-mediated defense mechanisms against pathogens in Caenorhabditis elegans.Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegansAge-dependent changes and biomarkers of aging in Caenorhabditis elegansNon-Coding RNAs in Caenorhabditis elegans Aging.Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteriaeIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
P50
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P50
description
onderzoeker
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researcher ORCID: 0000-0002-6103-156X
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name
Seung-Jae Lee
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Seung-Jae Lee
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Seung-Jae Lee
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Seung-Jae Lee
@nl
type
label
Seung-Jae Lee
@ast
Seung-Jae Lee
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Seung-Jae Lee
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Seung-Jae Lee
@nl
prefLabel
Seung-Jae Lee
@ast
Seung-Jae Lee
@en
Seung-Jae Lee
@es
Seung-Jae Lee
@nl
P108
P106
P1153
55892182100
P31
P496
0000-0002-6103-156X