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Characterisation of matrix vesicles in skeletal and soft tissue mineralisationCartilage to bone transitions in health and diseaseEndocrine role of bone: recent and emerging perspectives beyond osteocalcinHuman PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activitiesPHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fracturesLoss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcificationThe presence of PHOSPHO1 in matrix vesicles and its developmental expression prior to skeletal mineralizationFunctional involvement of PHOSPHO1 in matrix vesicle-mediated skeletal mineralization.The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells.Chondrocytes and longitudinal bone growth: the development of tibial dyschondroplasia.The distribution of elastin in developing and adult rat organs using immunocytochemical techniques.Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice.Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2-/- miceDesign, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.Extracellular matrix mineralization promotes E11/gp38 glycoprotein expression and drives osteocytic differentiationComparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily.Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes.Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes.Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting.A guide to modern quantitative fluorescent western blotting with troubleshooting strategiesRole of PHOSPHO1 in Periodontal Development and FunctionThe Functional co-operativity of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 during initiation of Skeletal Mineralization.Mechanisms and clinical consequences of vascular calcificationPhospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing.Pharmacological inhibition of PHOSPHO1 suppresses vascular smooth muscle cell calcification.Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (review).Endochondral Growth Defect and Deployment of Transient Chondrocyte Behaviors Underlie Osteoarthritis Onset in a Natural Murine ModelPhospholipase C-eta enzymes as putative protein kinase C and Ca2+ signalling components in neuronal and neuroendocrine tissues.Skeletal Mineralization Deficits and Impaired Biogenesis and Function of Chondrocyte-Derived Matrix Vesicles in Phospho1(-/-) and Phospho1/Pi t1 Double-Knockout Mice.Compounded PHOSPHO1/ALPL deficiencies reduce dentin mineralizationThe Expression of PHOSPHO1, nSMase2 and TNAP is Coordinately Regulated by Continuous PTH Exposure in Mineralising Osteoblast Cultures.Inflammatory cytokines and the GH/IGF-I axis: novel actions on bone growth.Ablation of osteopontin improves the skeletal phenotype of phospho1(-/-) mice.Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple TissuesThe effect of GH and IGF1 on linear growth and skeletal development and their modulation by SOCS proteins.The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling.Cartilage development and degeneration: a Wnt Wnt situation.Inflammation and linear bone growth: the inhibitory role of SOCS2 on GH/IGF-1 signaling.Pathophysiology and management of abnormal growth in children with chronic inflammatory bowel disease.Effects of choice of reverse-transcriptase enzyme and use of T4 gene 32 protein on banding patterns in agarose gel differential display.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Colin Farquharson
@ast
Colin Farquharson
@en
Colin Farquharson
@es
Colin Farquharson
@nl
type
label
Colin Farquharson
@ast
Colin Farquharson
@en
Colin Farquharson
@es
Colin Farquharson
@nl
prefLabel
Colin Farquharson
@ast
Colin Farquharson
@en
Colin Farquharson
@es
Colin Farquharson
@nl
P106
P21
P31
P496
0000-0002-4970-4039