Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
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Discovery of active enhancers through bidirectional expression of short transcriptsThe RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulatorSKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicingDeep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAsMutual relationships between transcription and pre-mRNA processing in the synthesis of mRNARegulated pre-mRNA splicing: the ghostwriter of the eukaryotic genomeRegulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanismsChromatin and epigenetic regulation of pre-mRNA processingA novel role for Cet1p mRNA 5'-triphosphatase in promoter proximal accumulation of RNA polymerase II in Saccharomyces cerevisiase.The yeast SR-like protein Npl3 links chromatin modification to mRNA processingCotranscriptional events in eukaryotic ribosome synthesisPELP1 oncogenic functions involve alternative splicing via PRMT6EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functionsPromoter-proximal pausing of RNA polymerase II: emerging roles in metazoansAssociations between intronic non-B DNA structures and exon skippingInhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus.Extremely fast and incredibly close: cotranscriptional splicing in budding yeast.Adventures in time and space: splicing efficiency and RNA polymerase II elongation rateWhy eukaryotic cells use introns to enhance gene expression: splicing reduces transcription-associated mutagenesis by inhibiting topoisomerase I cutting activity.Introduction to cotranscriptional RNA splicingModelling reveals kinetic advantages of co-transcriptional splicingGenome-Wide Analysis of Nascent Transcription in Saccharomyces cerevisiaeA quantitative, high-throughput reverse genetic screen reveals novel connections between Pre-mRNA splicing and 5' and 3' end transcript determinantsVezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II.Stable intronic sequence RNA (sisRNA), a new class of noncoding RNA from the oocyte nucleus of Xenopus tropicalis.Kinetic competition during the transcription cycle results in stochastic RNA processing.Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondriaMechanisms and Regulation of Alternative Pre-mRNA SplicingQuantification of pre-mRNA escape rate and synergy in splicing.A multi-exon-skipping detection assay reveals surprising diversity of splice isoforms of spinal muscular atrophy genes.Dynamic histone acetylation is critical for cotranscriptional spliceosome assembly and spliceosomal rearrangements.Detained introns are a novel, widespread class of post-transcriptionally spliced introns.Coupling mRNA processing with transcription in time and space.Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulationEfficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues.Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing.Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sampleDiverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast.Pre-mRNA splicing during transcription in the mammalian system.
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Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
description
article
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im November 2010 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2010
@uk
name
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
@en
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
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type
label
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
@en
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
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prefLabel
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
@en
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
@nl
P1433
P1476
Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons
@en
P2093
Fernando Carrillo Oesterreich
Karla M. Neugebauer
P304
P356
10.1016/J.MOLCEL.2010.11.004
P577
2010-11-01T00:00:00Z