Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction
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Mechanisms of Beta Cell Dysfunction Associated With Viral InfectionExpression of innate immunity genes and damage of primary human pancreatic islets by epidemic strains of Echovirus: implication for post-virus islet autoimmunity.CCL20 is elevated during obesity and differentially regulated by NF-κB subunits in pancreatic β-cells.Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity.Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cellsInduction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets.Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset.Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis.Effects of type 1 diabetes-associated IFIH1 polymorphisms on MDA5 function and expression.Echovirus plays major roles in the natural recombination of Coxsackievirus B3.Comparative and correlative assessments of cytokine, complement and antibody patterns in paediatric type 1 diabetes.Enterovirus infection is associated with an increased risk of childhood type 1 diabetes in Taiwan: a nationwide population-based cohort study.Pathophysiology of the pancreas after oral infection of genetically diverse mice with coxsackievirus B4-E2.α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation.A single amino acid substitution in viral VP1 protein alters the lytic potential of clone-derived variants of echovirus 9 DM strain in human pancreatic islets.Coxsackievirus-Induced Proteomic Alterations in Primary Human Islets Provide Insights for the Etiology of Diabetes.Epidemiology and Immune Pathogenesis of Viral SepsisUnexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells
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Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction
description
article
@en
im September 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2012
@uk
name
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@en
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@nl
type
label
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@en
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@nl
prefLabel
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@en
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@nl
P2093
P2860
P50
P1433
P1476
Enterovirus-induced gene expre ...... n pancreatic islet destruction
@en
P2093
A. Paananen
J. R. T. Lakey
M. Roivainen
P. Gopalacharyulu
P. Ylipaasto
R. Lahesmaa
S. Kaijalainen
T. Seppänen-Laakso
P2860
P2888
P304
P356
10.1007/S00125-012-2713-Z
P577
2012-09-16T00:00:00Z