Reactions and enzymes in the metabolism of drugs and other xenobiotics
about
XMetDB: an open access database for xenobiotic metabolismMarine invertebrate xenobiotic-activated nuclear receptors: their application as sensor elements in high-throughput bioassays for marine bioactive compoundsQSAR modeling: where have you been? Where are you going to?Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective EffectsIn silico mechanistic profiling to probe small molecule binding to sulfotransferasesBiotransformation and Oxidative Stress Responses in Captive Nile Crocodile (Crocodylus niloticus) Exposed to Organic Contaminants from the Natural Environment in South AfricaComputational tools and resources for metabolism-related property predictions. 1. Overview of publicly available (free and commercial) databases and softwareIn Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations.Triptolide Induces hepatotoxicity via inhibition of CYP450s in Rat liver microsomes.Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in ratsMonoamine oxidase A and B substrates: probing the pathway for drug development.Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes.Genetic and Non-genetic Factors Associated with Protein Abundance of Flavin-containing Monooxygenase 3 in Human Liver.Site of Metabolism Prediction Based on ab initio Derived Atom Representations.Metabolic profile and safety of piperlongumine.Modeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network.Drug-drug interaction and doping, part 1: an in vitro study on the effect of non-prohibited drugs on the phase I metabolic profile of toremifene.Deep Learning to Predict the Formation of Quinone Species in Drug Metabolism.Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.Identification of position isomers by energy-resolved mass spectrometry.Computational Approach to Structural Alerts: Furans, Phenols, Nitroaromatics, and Thiophenes.Phenotyping of CYP450 in human liver microsomes using the cocktail approach.Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes.Identification and characterization of metabolites of ASP015K, a novel oral Janus kinase inhibitor, in rats, chimeric mice with humanized liver, and humans.Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacologySinglet oxygen production and in vitro phototoxicity studies on fenofibrate, mycophenolate mofetil, trifusal, and their active metabolites
P2860
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P2860
Reactions and enzymes in the metabolism of drugs and other xenobiotics
description
im Juni 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 2012
@uk
name
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@en
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@nl
type
label
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@en
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@nl
prefLabel
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@en
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@nl
P1433
P1476
Reactions and enzymes in the metabolism of drugs and other xenobiotics
@en
P2093
Alessandro Pedretti
P304
P356
10.1016/J.DRUDIS.2012.01.017
P577
2012-06-01T00:00:00Z