about
MicroRNAs are involved in the self-renewal and differentiation of cancer stem cellsPanepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancerNiclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathwayIncreasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule TherapeuticsNovel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemopreventionA high-throughput screen for chemical inhibitors of exocytic transport in yeastSulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase GPharmacokinetics and pharmacodynamics of Phor21-betaCG(ala), a lytic peptide conjugate.Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix.A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.First International Conference on Chemoprevention of Prostate Cancer. Overview consensus statement.Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention.Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation.Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemopreventionSulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAsSuppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10.A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activitySulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletionA novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagyImmunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1αSuppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferationSynthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective.A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors.Effects of an unusual poison identify a lifespan role for Topoisomerase 2 in Saccharomyces cerevisiae.The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatmentNSAIDs inhibit tumorigenesis, but how?Mechanistic Role of MicroRNA in Cancer Chemoprevention by Nonsteroidal Anti-inflammatory Drugs.Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profilingNew hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres.Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex.NSAIDs: Old Drugs Reveal New Anticancer Targets.Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies.Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity.Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53.6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell lines.Modulating the cyclic guanosine monophosphate substrate selectivity of the phosphodiesterase 3 inhibitors by pyridine, pyrido[2,3-d]pyrimidine derivatives and their effects upon the growth of HT-29 cancer cell line.Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Gary A Piazza
@ast
Gary A Piazza
@en
Gary A Piazza
@es
Gary A Piazza
@nl
type
label
Gary A Piazza
@ast
Gary A Piazza
@en
Gary A Piazza
@es
Gary A Piazza
@nl
prefLabel
Gary A Piazza
@ast
Gary A Piazza
@en
Gary A Piazza
@es
Gary A Piazza
@nl
P106
P31
P496
0000-0003-4418-887X