about
Hypoplastic left heart syndrome: knowledge discovery with a data mining approach.The ClC-3 Cl-/H+ antiporter becomes uncoupled at low extracellular pHA differential role for endocytosis in receptor-mediated activation of Nox1.Electrophysiology of reactive oxygen production in signaling endosomesActivation of swelling-activated chloride current by tumor necrosis factor-alpha requires ClC-3-dependent endosomal reactive oxygen productionSurfactant-associated protein A provides critical immunoprotection in neonatal mice.Characterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging.Endothelial cell tolerance to lipopolysaccharide challenge is induced by monophosphoryl lipid A.Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.Placental HSD2 Expression and Activity Is Unaffected by Maternal Protein Consumption or Gender in C57BL/6 Mice.Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning.Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice.Newborn lamb coronary artery reactivity is programmed by early gestation dexamethasone before the onset of systemic hypertension.LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.Inhibition of endocytosis exacerbates TNF-α-induced endothelial dysfunction via enhanced JNK and p38 activation.Overexpression of CLC-3 in HEK293T cells yields novel currents that are pH dependent.Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3.c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells.A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation.Regulation of arterial reactivity by concurrent signaling through the E-prostanoid receptor 3 and angiotensin receptor 1.Endothelial superoxide production is altered in sheep programmed by early gestation dexamethasone exposure.Pediatric posterior reversible encephalopathy syndrome presenting with isolated cerebellar edema and obstructive hydrocephalus.Potentiation and tolerance of toll-like receptor priming in human endothelial cells.Residual lesions in postoperative pediatric cardiac surgery patients receiving extracorporeal membrane oxygenation support.CLC-3 channels modulate excitatory synaptic transmission in hippocampal neurons.Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.Standardizing ICU management of pediatric traumatic brain injury is associated with improved outcomes at discharge.Basolateral chloride current in human airway epithelia.Early gestation dexamethasone alters baroreflex and vascular responses in newborn lambs before hypertensionRenovascular hypertension in mice with brain-selective overexpression of AT1a receptors is buffered by increased nitric oxide production in the peripheryMurine aortic reactivity is programmed equally by maternal low protein diet or late gestation dexamethasoneLocalising oxidant "stress" in the antiphospholipid syndromeModulation of ClC-3 gating and proton/anion exchange by internal and external protons and the anion selectivity filter
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description
onderzoeker
@nl
pediatrician
@en
հետազոտող
@hy
name
Fred S Lamb
@ast
Fred S Lamb
@es
Fred S Lamb
@nl
Fred S. Lamb
@en
type
label
Fred S Lamb
@ast
Fred S Lamb
@es
Fred S Lamb
@nl
Fred S. Lamb
@en
prefLabel
Fred S Lamb
@ast
Fred S Lamb
@es
Fred S Lamb
@nl
Fred S. Lamb
@en
P108
P106
P21
P31
P496
0000-0003-2955-5133