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Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine ModelCXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltrationIs the beta3-adrenoceptor (ADRB3) a potential target for uterorelaxant drugs?Oxidative stress and pulmonary inflammation: pharmacological intervention with antioxidants.Evaluation of the quality of publications on randomized clinical trials using the Consolidated Standards of Reporting Trials (CONSORT) statement guidelines in a Spanish tertiary hospital.Cigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequencesPhosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells.Evaluation of Mucociliary Clearance by Three Dimension Micro-CT-SPECT in Guinea Pig: Role of Bitter Taste Agonists.Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile.The human near-term myometrial beta 3-adrenoceptor but not the beta 2-adrenoceptor is resistant to desensitisation after sustained agonist stimulation.Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist.Mucus and MUC in asthma.MUC4 impairs the anti-inflammatory effects of corticosteroids in patients with chronic rhinosinusitis with nasal polyps.Selective Inhibition of Phosphodiesterases 4A, B, C and D Isoforms in Chronic Respiratory Diseases: Current and Future Evidences.Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability.Retinoid X receptor agonists impair arterial mononuclear cell recruitment through peroxisome proliferator-activated receptor-γ activation.Piclamilast inhibits the pro-apoptotic and anti-proliferative responses of A549 cells exposed to H(2)O(2) via mechanisms involving AP-1 activation.Bafetinib inhibits functional responses of human eosinophils in vitro.N-acetyl-L-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory mediators in alveolar type II epithelial cells infected with influenza virus A and B and with respiratory syncytial virus (RSV).Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis.Stimulation of the ADRB3 adrenergic receptor induces relaxation of human placental arteries: influence of preeclampsia.Effect of two phenanthrene alkaloids on angiotensin II-induced leukocyte-endothelial cell interactions in vivo.Biotransformation in vitro of the 22R and 22S epimers of budesonide by human liver, bronchus, colonic mucosa and skin.Aclidinium inhibits human lung fibroblast to myofibroblast transition.Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injuryP-selectin upregulation in bleomycin induced lung injury in rats: effect of N-acetyl-L-cysteine.A small molecule, orally active, alpha4beta1/alpha4beta7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats.Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients.Increased lung neutrophil apoptosis and inflammation resolution in nonresponding pneumonia.Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.Palliative treatment of dyspnea with epidural methadone in advanced emphysema.Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.Extracellular calcium-sensing receptor mediates human bronchial epithelial wound repair.Relaxation by beta 3-adrenoceptor agonists of the isolated human internal anal sphincter.Erythromycin exerts in vivo anti-inflammatory activity downregulating cell adhesion molecule expression.Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells.Histamine up-regulates phosphodiesterase 4 activity and reduces prostaglandin E2-inhibitory effects in human neutrophils.Vascular effects of the new anti-migraine agent almotriptan on human cranial and peripheral arteries.Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.Oral N-acetylcysteine attenuates the rat pulmonary inflammatory response to antigen.
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Esteban Morcillo
@ast
Esteban Morcillo
@en
Esteban Morcillo
@es
Esteban Morcillo
@nl
type
label
Esteban Morcillo
@ast
Esteban Morcillo
@en
Esteban Morcillo
@es
Esteban Morcillo
@nl
prefLabel
Esteban Morcillo
@ast
Esteban Morcillo
@en
Esteban Morcillo
@es
Esteban Morcillo
@nl
P106
P21
P31
P496
0000-0003-4373-9457