about
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage.Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activitiesAromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells.A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.Tibialis anterior muscle needle biopsy and sensitive biomolecular methods: a useful tool in myotonic dystrophy type 1On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium saltsEvidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.Perylene and coronene derivatives binding to G-rich promoter oncogene sequences efficiently reduce their expression in cancer cells.High-sensitive cardiac troponin T (hs-cTnT) assay as serum biomarker to predict cardiac risk in myotonic dystrophy: A case-control study.Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.Evidence for G-quadruplex in the promoter of VEGFR-2 and its targeting to inhibit tumor angiogenesis.Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell DeathPharmacological activation of SIRT6 triggers lethal autophagy in human cancer cellsInsights into telomeric G-quadruplex DNA recognition by HMGB1 proteinTailoring a lead-like compound targeting multiple G-quadruplex structures
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Sara Iachettini
@ast
Sara Iachettini
@en
Sara Iachettini
@es
Sara Iachettini
@nl
type
label
Sara Iachettini
@ast
Sara Iachettini
@en
Sara Iachettini
@es
Sara Iachettini
@nl
prefLabel
Sara Iachettini
@ast
Sara Iachettini
@en
Sara Iachettini
@es
Sara Iachettini
@nl
P106
P21
P31
P496
0000-0002-9442-0326