about
How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?Disrupted lymph node and splenic stroma in mice with induced inflammatory melanomas is associated with impaired recruitment of T and dendritic cells.The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cellsIFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomasMolecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.Temporal cross-talk between TCR and STAT signals for CD8 T cell effector differentiation.In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation.Distinct patterns of cytolytic T-cell activation by different tumour cells revealed by Ca2+ signalling and granule mobilization.Active STAT5 regulates T-bet and eomesodermin expression in CD8 T cells and imprints a T-bet-dependent Tc1 program with repressed IL-6/TGF-β1 signaling.Silence STAT3 in the procancer niche… and activate CD8+ T cells to kill premetastatic myeloid intruders.Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexesActivated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanomaImmunosuppression in inflammatory melanoma: can it be resisted by adoptively transferred T cells?Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regressionMembrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression
P50
Q27644089-63DAD703-3E86-4214-A7C4-ADC1A03429B4Q33980128-C277781B-978C-4A7D-9B41-81021B8DB7EFQ34002457-7509196B-E4F6-4E02-9C51-C0923AF66734Q35507485-484A2F6A-613C-4F50-8E3C-00AD5A95894AQ36000835-6245A59D-4D01-434D-9273-4D97ED34A7DCQ36656068-5BF5E666-91E8-47E2-B2C2-5133D82F03B6Q36783899-6472EE3A-96E2-46B5-9697-801D88A1D292Q38734283-00FB29B1-595E-48A5-A256-0B406636C6C9Q39100059-624F87A4-13AF-47B0-A968-C12B0328BC9AQ41730548-59A45EB5-741D-4979-8089-752F8044A100Q50740568-8994DF5C-D5F9-4867-BE6A-01301EF30F28Q57275451-ADD46A43-0294-4008-B09B-E5E4B7A66CEDQ82419683-D7E42C8B-4695-4935-9E4F-78839C06532BQ85631729-0D5D7295-695B-43F2-9BA4-35B9FF313D8DQ92376163-15179378-5C72-440E-9E35-9EB49F6940B3Q92728069-17BD3F75-9878-4BB7-8905-9AE28EAD98A9
P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Nathalie Auphan-Anezin
@ast
Nathalie Auphan-Anezin
@en
Nathalie Auphan-Anezin
@es
Nathalie Auphan-Anezin
@nl
type
label
Nathalie Auphan-Anezin
@ast
Nathalie Auphan-Anezin
@en
Nathalie Auphan-Anezin
@es
Nathalie Auphan-Anezin
@nl
prefLabel
Nathalie Auphan-Anezin
@ast
Nathalie Auphan-Anezin
@en
Nathalie Auphan-Anezin
@es
Nathalie Auphan-Anezin
@nl
P106
P1153
15622897800
P21
P31
P496
0000-0002-1967-5206