Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
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Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposureIsolated populations and complex disease gene identificationLoss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin diseaseA diversity profile of the human skin microbiotaRecent advances in understanding ichthyosis pathogenesisProbiotics and Atopic Dermatitis: An OverviewNanoparticle-Enabled Transdermal Drug Delivery Systems for Enhanced Dose Control and Tissue TargetingFilaggrin failure - from ichthyosis vulgaris to atopic eczema and beyondDeimination of human filaggrin-2 promotes its proteolysis by calpain 1Filaggrin in the frontline: role in skin barrier function and diseaseTemporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitisThe human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the 'fused genes' familyMicrobial ecology of the skin in the era of metagenomics and molecular microbiologyTmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjectsWhole-genome sequencing in an autism multiplex familyFilaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptensLD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort.Pharmacogenetics and personal genomes.Mast cells in atopic dermatitisA milieu of regulatory elements in the epidermal differentiation complex syntenic block: implications for atopic dermatitis and psoriasis.Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohortA homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.An update on the genetics of atopic dermatitis: scratching the surface in 2009.Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis.Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.Effectiveness and cost-effectiveness of daily all-over-body application of emollient during the first year of life for preventing atopic eczema in high-risk children (The BEEP trial): protocol for a randomised controlled trial.Retapamulin 1% Ointment and Clobetasol Propionate 0.05% Foam is More Efficacious than Vehicle Ointment and Clobetasol 0.05% Propionate Foam in the Treatment of Hand/Foot Dermatitis: A Single Center, Randomized, Double-blind Study.Regulation of the dynamic chromatin architecture of the epidermal differentiation complex is mediated by a c-Jun/AP-1-modulated enhancer.Filaggrin genotype determines functional and molecular alterations in skin of patients with atopic dermatitis and ichthyosis vulgaris.Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis preventionResearch statistics in atopic eczema: what disease is this?Common FLG mutation K4671X not associated with atopic dermatitis in Han Chinese in a family association studyGenetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitisMicrobiome in atopic dermatitis[The ichthyoses. Pathophysiological models of epidermal differentiation].Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutationsThe allergy gene: how a mutation in a skin protein revealed a link between eczema and asthma.Atopic dermatitis in children: clinical features, pathophysiology, and treatment
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Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
description
article
@en
im April 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2007
@uk
name
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@en
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@nl
type
label
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@en
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@nl
prefLabel
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@en
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@nl
P2093
P50
P356
P1433
P1476
Comprehensive analysis of the ...... sis vulgaris and atopic eczema
@en
P2093
Aileen Sandilands
Alan T Evans
Ana Terron-Kwiatkowski
Colin S Munro
Frances J D Smith
Gráinne M O'Regan
Haihui Liao
Ivo Nagtzaam
Linda E Campbell
Michel van Geel
P2888
P304
P356
10.1038/NG2020
P407
P50
P577
2007-04-08T00:00:00Z