about
FREAC-1 contains a cell-type-specific transcriptional activation domain and is expressed in epithelial-mesenchymal interfacesA forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicleThe human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIBDifferential activation of lung-specific genes by two forkhead proteins, FREAC-1 and FREAC-2Forkhead transcription factors: key players in development and metabolismExpression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle.PXL01 in sodium hyaluronate for improvement of hand recovery after flexor tendon repair surgery: randomized controlled trialRegulation of the muscle-specific AMP-activated protein kinase alpha2beta2gamma3 complexes by AMP and implications of the mutations in the gamma3-subunit for the AMP dependence of the enzyme.Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis.The novel antimicrobial peptide PXL150 in the local treatment of skin and soft tissue infections.Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model.Antimicrobial Peptides: An Emerging Category of Therapeutic Agents.PXL01 in sodium hyaluronate results in increased PRG4 expression: a potential mechanism for anti-adhesion.Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.The two-exon gene of the human forkhead transcription factor FREAC-2 (FKHL6) is located at 6p25.3.STK25 is a critical determinant in nonalcoholic steatohepatitis.Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes.AMP-activated protein kinase inhibits IL-6-stimulated inflammatory response in human liver cells by suppressing phosphorylation of signal transducer and activator of transcription 3 (STAT3).Effect of lactoferrin peptide (PXL01) on rabbit digit mobility after flexor tendon repair.Anti-infective efficacy of the lactoferrin-derived antimicrobial peptide HLR1r.Protein kinase STK25 aggravates the severity of non-alcoholic fatty pancreas disease in mice.Efficacy and safety profile of the novel antimicrobial peptide PXL150 in a mouse model of infected burn wounds.Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained.The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle.Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity.Effects of calcineurin activation on insulin-, AICAR- and contraction-induced glucose transport in skeletal muscle.Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle.Opposite transcriptional regulation in skeletal muscle of AMP-activated protein kinase gamma3 R225Q transgenic versus knock-out mice.Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet.Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.Erratum to "Anti-infective efficacy of the lactoferrin-derived antimicrobial peptide HLR1r" [Peptides vol. 81 (2016) 21-28].Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH.Characterization of the in vitro, ex vivo, and in vivo Efficacy of the Antimicrobial Peptide DPK-060 Used for Topical Treatment.Administration of Lactobacillus evokes coordinated changes in the intestinal expression profile of genes regulating energy homeostasis and immune phenotype in miceA lactoferrin-derived peptide (PXL01) for the reduction of adhesion formation in flexor tendon surgery: an experimental study in rabbitsA novel polypeptide derived from human lactoferrin in sodium hyaluronate prevents postsurgical adhesion formation in the ratFibroblast growth factor 21 signaling: The liver in focusTargeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver DiseaseLipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Margit Mahlapuu
@ast
Margit Mahlapuu
@en
Margit Mahlapuu
@es
Margit Mahlapuu
@nl
type
label
Margit Mahlapuu
@ast
Margit Mahlapuu
@en
Margit Mahlapuu
@es
Margit Mahlapuu
@nl
prefLabel
Margit Mahlapuu
@ast
Margit Mahlapuu
@en
Margit Mahlapuu
@es
Margit Mahlapuu
@nl
P106
P31
P496
0000-0001-8740-8874