Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

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Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

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im Januar 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 19 September 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Partial Mechanical Unloading o ...... oceptor Signaling Microdomains

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Anita Alvarez-Laviada

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Carla Lucarelli

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Cesare M Terracciano

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Claire E Poulet

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Giuseppe Faggian

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Jose L Sanchez-Alonso

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Sean O Bello

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P2860

Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis

Bridge to removal: a paradigm shift for left ventricular assist device therapy.

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure.

T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure.

Prolonged mechanical unloading affects cardiomyocyte excitation-contraction coupling, transverse-tubule structure, and the cell surface.

Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading.

Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes.

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling.

Evolution of β-blockers: from anti-anginal drugs to ligand-directed signalling.

Cardiomyocyte Ca2+ handling and structure is regulated by degree and duration of mechanical load variation.

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1302

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scholarly article

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10.3389/FPHYS.2018.01302

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English

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Julia V. Gorelik

Peter T Wright

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2018-09-19T00:00:00Z

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30283354

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6157487

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