Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques
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Mechanisms of HIV protein degradation into epitopes: implications for vaccine designA global approach to HIV-1 vaccine developmentAltered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.Safety and tolerability of conserved region vaccines vectored by plasmid DNA, simian adenovirus and modified vaccinia virus ankara administered to human immunodeficiency virus type 1-uninfected adults in a randomized, single-blind phase I trial.HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaquesCharacterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c miceComparison of neutralizing antibody responses elicited from highly diverse polyvalent heterotrimeric HIV-1 gp140 cocktail immunogens versus a monovalent counterpart in rhesus macaquesBroad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adultsEarly Kinetics of the HLA Class I-Associated Peptidome of MVA.HIVconsv-Infected Cells.Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes.Humoral responses to HIVconsv induced by heterologous vaccine modalities in rhesus macaques.Antigenicity and immunogenicity of transmitted/founder, consensus, and chronic envelope glycoproteins of human immunodeficiency virus type 1Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice.Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV/NDK challenge virus loadModulation of HIV-1 immunity by adjuvants.Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines.Development of an epitope-based HIV-1 vaccine strategy from HIV-1 lipopeptide to dendritic-based vaccines.Full-length HIV-1 immunogens induce greater magnitude and comparable breadth of T lymphocyte responses to conserved HIV-1 regions compared with conserved-region-only HIV-1 immunogens in rhesus monkeys.Dendritic cell immunotherapy.HIV Vaccination: A Roadmap among Advancements and Concerns.
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Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques
description
article
@en
im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2012
@uk
name
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@en
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@nl
type
label
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@en
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@nl
prefLabel
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@en
Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
@nl
P2093
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Prime-boost regimens with adju ...... d regions of HIV-1 in macaques
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P2093
Alfredo Nicosia
Alice Mbewe-Mvula
Andrew J. McMichael
Cornelis J.M. Melief
Esther D. Quakkelaar
Guillaume B. Stewart-Jones
Jan W. Drijfhout
Maximillian Rosario
Nicola Borthwick
Stefano Colloca
P304
P356
10.1097/QAD.0B013E32834ED9B2
P407
P577
2012-01-01T00:00:00Z