Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLö-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig

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Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLö-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig

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http://www.wikidata.org/entity/Q57095530

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im September 2018 veröffentlicher wissenschaftlicher Artikel

@de

scientific article published on 26 July 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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name

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

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Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

@nl

type

Item

label

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

@en

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

@nl

prefLabel

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

@en

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

@nl

P1476

Evaluating the broad-spectrum ...... d VX in the Hartley guinea pig

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P2093

Christina M Wilhelm

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David A Jett

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Gennady E Platoff

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Michael C Babin

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Thomas H Snider

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P2860

Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment.

A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides.

Management of acute organophosphorus pesticide poisoning

Limitations and challenges in treatment of acute chemical warfare agent poisoning.

Chemical warfare agents: II. Nerve agents.

Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes.

Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig.

The value of novel oximes for treatment of poisoning by organophosphorus compounds.

Investigation of the reactivation kinetics of a large series of bispyridinium oximes with organophosphate-inhibited human acetylcholinesterase.

Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime+HI-6: Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics.

P304

142-148

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P31

scholarly article

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10.1016/J.NEURO.2018.07.014

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P407

English

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P50

David T Yeung

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2018-07-26T00:00:00Z

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P698

30056178

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P921

toxicology

P932

6153028

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