about
Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivoEngineering CHO cell growth and recombinant protein productivity by overexpression of miR-7.MiR-7 triggers cell cycle arrest at the G1/S transition by targeting multiple genes including Skp2 and Psme3.A Bioinformatics Pipeline for the Identification of CHO Cell Differential Gene Expression from RNA-Seq Data.Detection and cloning of LINE-1 elements in CHO cells.Targeted genetic modification of cell lines for recombinant protein production.CHO microRNA engineering is growing up: recent successes and future challenges.The human L1 element: a potential biomarker in cancer prognosis, current status and future directions.Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors.Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling.Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells.Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction.CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.Regulating bioactivity of Cu2+ bis-1,10-phenanthroline artificial metallonucleases with sterically functionalized pendant carboxylates.Potent oxidative DNA cleavage by the di-copper cytotoxin: [Cu2(μ-terephthalate)(1,10-phen)4]2+.Microarray expression profiling identifies genes regulating sustained cell specific productivity (S-Qp) in CHO K1 production cell lines.Development and characterization of a Chinese hamster ovary cell-specific oligonucleotide microarray.Predicting cell-specific productivity from CHO gene expression.Decreasing Txnip mRNA and protein levels in pancreatic MIN6 cells reduces reactive oxygen species and restores glucose regulated insulin secretion.Microarray and proteomics expression profiling identifies several candidates, including the valosin-containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines.Identification of a novel, functional role for S100A13 in invasive lung cancer cell lines.Directed differentiation of mouse embryonic stem cells into pancreatic-like or neuronal- and glial-like phenotypes.Initial identification of low temperature and culture stage induction of miRNA expression in suspension CHO-K1 cells.Detecting de novo insulin synthesis in embryonic stem cell-derived populations.Resistance to multiple steroids in two sisters.Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine.Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.Exploring the Potential Application of Short Non-Coding RNA-Based Genetic Circuits in Chinese Hamster Ovary Cells.Impact of miR-7 over-expression on the proteome of Chinese hamster ovary cells.Copper phenanthrene oxidative chemical nucleases.Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling.Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.Utilization and evaluation of CHO-specific sequence databases for mass spectrometry based proteomics.Radical-induced purine lesion formation is dependent on DNA helical topology.Antimicrobial Peptide Production and Purification.Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14Resistance to several steroids in two sisters
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Niall Barron
@ast
Niall Barron
@en
Niall Barron
@es
Niall Barron
@nl
type
label
Niall Barron
@ast
Niall Barron
@en
Niall Barron
@es
Niall Barron
@nl
prefLabel
Niall Barron
@ast
Niall Barron
@en
Niall Barron
@es
Niall Barron
@nl
P108
P106
P1153
55163929400
P31
P496
0000-0003-4602-326X