Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor (BMPR1A) Fusion Protein Increases Bone Mass and Bone Formation in Mice Subjected to Hindlimb Unloading

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Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor (BMPR1A) Fusion Protein Increases Bone Mass and Bone Formation in Mice Subjected to Hindlimb Unloading

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http://www.wikidata.org/entity/Q57151981

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2017

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Treatment With a Soluble Bone ...... ubjected to Hindlimb Unloading

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Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor

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Treatment With a Soluble Bone ...... ubjected to Hindlimb Unloading

@en

Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor

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Treatment With a Soluble Bone ...... ubjected to Hindlimb Unloading

@en

Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor

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P1476

Treatment With a Soluble Bone ...... ubjected to Hindlimb Unloading

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P2093

Chrissy Conlon

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Daniel Grasso

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Daniel J Brooks

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Frank C Ko

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J Ignacio Aguirre

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Jordan M Spatz

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Miranda Van Vliet

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Rachel Ellman

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Thomas J Wronski

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P2860

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

WNT signaling in bone homeostasis and disease: from human mutations to treatments

Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading

Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass.

Caloric restriction leads to high marrow adiposity and low bone mass in growing mice

Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.

Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.

A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.

Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in mouse

Space flight calcium: implications for astronaut health, spacecraft operations, and Earth.

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66-72

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scholarly article

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10.1002/JBM4.10012

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English

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P478

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Mary L Bouxsein

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2017-10-01T00:00:00Z

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P698

30283882

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P921

morphogenesis

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6124165

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